Results 91 to 100 of about 8,490,622 (305)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Heat transfer and pressure drop in tape generated swirl flow [PDF]
, 1967 The heat transfer and pressure drop characteristics of water in tape generated swirl flow were investigated. The test sections were electrically heated small diameter nickel tubes with tight fitting full length Inconel tapes of twist ratios from 2. 48 to
Lopina, Robert F., Bergles A. E.
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Study on Flow Boiling Heat Transfer Characteristics of R404A in Small-diameter Tubes
Zhileng xuebao, 2018 The flow boiling heat transfer process of R404A in small-diameter tubes is a very complex physical phenomenon. At present, research on the heat transfer characteristics of R404A is mostly focused on large-diameter tubes, and there has been little ...
Wang Xuedong, Liu Jianhua, Han Saisai
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Zhileng xuebao, 2012 The three dimensional physical model and mathematical model of turbulent flow and heat transfer in the channel of honeycombed plate heat exchanger were established, and the corresponding flow field and temperature field was numerically simulated.
Li Longjian, Chen Huan, Wu Zhijuan
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Post critical heat transfer to flowing liquid in a vertical tube [PDF]
, 1974 Sponsored by National Science Foundation Contract no. NSF GK-17745, D.S.R.
Plummer, David N.
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Study on Heat Transfer and Friction Characteristics of Sinusoidal Wavy Type Cooling Coil
Zhileng xuebao, 2007 Wavy fin has been applied in evaporators, condensers and terminal equipment heat exchangers of central air conditioning because of its good heat transfer and friction behavior. Sinusoidal wavy fin type cooling coil of central air conditioning was studied
高强, 王秋旺, 王家贵
doaj +2 more sources
Experimental Investigation of Microchannel Heat Sink with Modified Hexagonal Fins
Journal of Applied Fluid Mechanics, 2019 The concept of periodic renewal of boundary layers is a promising technique for the enhancement of heat transfer in microchannels. Extending the above concept, microchannel heatsink with modified hexagonal fins has been proposed for disrupting the flow ...
S. Subramanian +2 more
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