Results 71 to 80 of about 8,490,622 (305)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Heat transfer during film condensation of potassium vapor [PDF]
, 1966 The object of this work is to investigate theoretically and experimentally the following two phases of heat transfer during condensation of potassium vapore, a.
Kroger, Detlev Gustav
core
The design of mini/micro heat exchangers: A world of opportunities and constraints [PDF]
, 2018 Micro heat exchangers and heat sinks broadened their use in many technological fields during the last two decades. The reduction of the dimensions of the channels allows to obtain ultra-compact heat exchangers characterized by higher surface-to-volume ...
Gian Luca Morini +5 more
core +1 more source
Zhileng xuebao, 2016 Experiments are performed in rectangular micro-channels (dH =0.293 mm) under the condition of different mass flux and heat flux to evaluate the flow boiling heat transfer characteristics with deionized water and anhydrous ethanol.
Chen Yumin, Liu Dongyao
doaj
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Subcooled flow boiling of fluorocarbons [PDF]
, 1971 A study was conducted of heat transfer and hydrodynamic behavior for subcooled flow boiling of Freon-113, one of a group of fluorocarbons suitable for use in cooling of high-power-density electronic components. Problems arising from the excellent wetting
Bergles A. E., Murphy, Richard Walter
core
Experimental Study for Heat Transfer Characteristics of Vertical Rectangular Narrow Channels
Zhileng xuebao, 2014 Ionized water was used to investigate the heat transfer characteristics of vertical rectangular narrow channels experimentally. The distribution characteristics of wall-temperature and the local heat transfer coefficient were analyzed by using single ...
Liu Xiaode +3 more
doaj
A Study on Heat-Transfer Characteristics by a Ground-Heating Method [PDF]
Sustainability, 2018 The ground-heating method using the electric heating pipe improves many problems of the conventional soft-ground improvement method and the ground-heating method using fossil fuel. However, in order to use this method practically, it is necessary to experimentally verify the temperature change due to the discharge of water vapor, and also to compare ...
openaire +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Tables for solution of the heat-conduction equation with a time-dependent heating rate [PDF]
, 1962 Tables are presented for the solution of the transient onedimensional heat flow in a solid body of constant material properties with the heating rate at one boundary dependent on time. These tables allow convenient and rapid estimation of the temperature
Bergles A. E.
core