Results 61 to 70 of about 184,279 (267)

Experimental Study on the Boiling Heat Transfer Characteristics in Micro-channel with Two Different Working Medium

open access: yesZhileng xuebao, 2016
Experiments are performed in rectangular micro-channels (dH =0.293 mm) under the condition of different mass flux and heat flux to evaluate the flow boiling heat transfer characteristics with deionized water and anhydrous ethanol.
Chen Yumin, Liu Dongyao
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Experimental Study for Heat Transfer Characteristics of Vertical Rectangular Narrow Channels

open access: yesZhileng xuebao, 2014
Ionized water was used to investigate the heat transfer characteristics of vertical rectangular narrow channels experimentally. The distribution characteristics of wall-temperature and the local heat transfer coefficient were analyzed by using single ...
Liu Xiaode   +3 more
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Cross-Scale Simulation Study of Porous Medium Heat Exchangers Based on Reliable Cell Selection

open access: yesEnergies
This study compares the heat transfer and pressure drop of three cell structures, namely Kelvin cells (KCs), ellipsoidal Kelvin cells (EKCs), and body-centered cubic (BCC) structures, at the cell scale in order to identify the superior configuration ...
Yiqiang Liang   +4 more
doaj   +1 more source

A Study on Heat-Transfer Characteristics by a Ground-Heating Method [PDF]

open access: yesSustainability, 2018
The ground-heating method using the electric heating pipe improves many problems of the conventional soft-ground improvement method and the ground-heating method using fossil fuel. However, in order to use this method practically, it is necessary to experimentally verify the temperature change due to the discharge of water vapor, and also to compare ...
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Research on Fluid Flow and Heat Transfer Characteristics in Channel of Honeycombed Plate Heat Exchanger

open access: yesZhileng xuebao, 2012
The three dimensional physical model and mathematical model of turbulent flow and heat transfer in the channel of honeycombed plate heat exchanger were established, and the corresponding flow field and temperature field was numerically simulated.
Li Longjian, Chen Huan, Wu Zhijuan
doaj  

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