Results 101 to 110 of about 1,201,680 (348)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Local heating effects on flow and heat transfer in microchannels [PDF]
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +2 more
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Forced convection and flow boiling with and without enhancement devices for top-side-heated horizontal channels [PDF]
The effect of enhancement devices on flow boiling heat transfer in coolant channels, which are heated either from the top side or uniformly was studied.
Boyd, Ronald D., Sr., Turknett, Jerry C.
core +1 more source
Research on Impinging Jet [PDF]
, 2001 Impinging jet is very useful for heat transfer and mass transfer enhancement. Historical research process on the impinging jet heat transfer is described systematically. The present paper is composed of two stages.
サカキバラ ジュン +2 more
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Numerical simulation of heat transfer to separation tio(2)/water nanofluids flow in an asymmetric abrupt expansion [PDF]
, 2015 Flow separation and reattachment of 0.2% TiO2 nanofluid in an asymmetric abrupt expansion is studied in this paper. Such flows occur in various engineering and heat transfer applications.
Al-Shamma'a, A +6 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
An Overview of the Recent Advances in Pool Boiling Enhancement Materials, Structrure, and Devices
MicromachinesThis review attempts to provide a comprehensive assessment of recent methodologies, structures, and devices for pool boiling heat transfer enhancement. Several enhancement approaches relating to the underlying fluid route and the capability to eliminate ...
José Pereira +4 more
doaj +1 more source
Numerical Analysis of Turbulent Flow and Heat Transfer in Internally Finned Tubes
Frontiers in Energy Research, 2019 In this study, single-phase heat transfer enhancement in internally finned tubes is investigated numerically. The influence of fin number, helix angle, fin height, fin width, and shape on the flow and heat transfer characteristics is studied.
Zhanwei Liu +3 more
doaj +1 more source