Results 81 to 90 of about 383,269 (259)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Numerical Analysis of Turbulent Flow and Heat Transfer in Internally Finned Tubes

open access: yesFrontiers in Energy Research, 2019
In this study, single-phase heat transfer enhancement in internally finned tubes is investigated numerically. The influence of fin number, helix angle, fin height, fin width, and shape on the flow and heat transfer characteristics is studied.
Zhanwei Liu   +3 more
doaj   +1 more source

Hidden heat transfer in equilibrium states implies directed motion in nonequilibrium states

open access: yes, 2006
We study a class of heat engines including Feynman's ratchet, which exhibits a directed motion of a particle in nonequilibrium steady states maintained by two heat baths.
Naoko Nakagawa   +4 more
core   +1 more source

Growth Dynamics During Dropwise Condensation on Nanostructured Superhydrophobic Surfaces [PDF]

open access: yes, 2019
Condensation on superhydrophobic nanostructured surfaces offers new opportunities for enhanced energy conversion, efficient water harvesting, and high performance thermal management.
Enright, Ryan   +2 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

An Overview of the Recent Advances in Pool Boiling Enhancement Materials, Structrure, and Devices

open access: yesMicromachines
This review attempts to provide a comprehensive assessment of recent methodologies, structures, and devices for pool boiling heat transfer enhancement. Several enhancement approaches relating to the underlying fluid route and the capability to eliminate ...
José Pereira   +4 more
doaj   +1 more source

Effect of heated wall inclination on natural convection heat transfer in water with near-wall injection of millimeter-sized bubbles [PDF]

open access: yes, 2017
Natural convection heat transfer from a heated wall in water with near-wall injection of millimeter-sized bubbles is studied experimentally. Velocity and temperature measurements are conducted in the nearwall region.
Denissenko, Petr   +2 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Effect of the angle of attack of a rectangular wing on the heat transfer enhancement in channel flow at low Reynolds number [PDF]

open access: yes, 2017
Convective heat transfer enhancement can be achieved by generating secondary flow structures that are added to the main flow to intensify the fluid exchange between hot and cold regions.
A. Khanjian   +4 more
core   +3 more sources

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