Results 71 to 80 of about 383,269 (259)
Experimental studies on heat transfer augmentation using twisted aluminium taper clips and twisted tapes [PDF]
, 2007 Heat exchangers have several industrial and engineering applications. The design procedure of heat exchangers is quite complicated, as it needs exact analysis of heat transfer rate and pressure drop estimations apart from issues such as long-term ...
Mohapatra, Vivek Chandan, Sahu, Debashis
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 2011 We demonstrate the possibility of achieving enhanced frequency-selective near-field radiative heat transfer between patterned (photonic crystal) slabs at designable frequencies and separations, exploiting a general numerical approach for computing heat ...
Alejandro W. Rodriguez +8 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Numerical study of an exhaust heat recovery system using corrugated tubes and twisted tape inserts [PDF]
, 2014 Thesis (M.S.) University of Alaska Fairbanks, 2014Diesel engine generators are the major power source for small communities in cold regions. Diesel generators waste about 1/3 of their fuel energy in the form of heat through exhaust gas.
Mokkapati, Vamsi Krishna Sarma
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
An Experimental Study on the Heat Enhancement and the Bio-Heat Transfer Using Gold Macro Road and Ultrasound: A Potential Alternative to Kill Cancer Cells [PDF]
, 2014 We have previously proposed a method of treating solid tumors with a combination of gold macro-rods irradiated with ultrasound. Macro particle sized rods offer a greater circumferential treatment area over nanoparticle options.
Austerlitz, C. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Forced convection and flow boiling with and without enhancement devices for top-side-heated horizontal channels [PDF]
The effect of enhancement devices on flow boiling heat transfer in coolant channels, which are heated either from the top side or uniformly was studied.
Boyd, Ronald D., Sr., Turknett, Jerry C.
core +1 more source