Results 51 to 60 of about 383,269 (259)
Thermal Analysis of a Solar External Receiver Tube with a Novel Component of Guide Vanes
Energies, 2021 The heat transfer performance of a solar external receiver tube with guide vanes was numerically studied under non-uniform heat flux conditions. Models of the smooth tube and the tube with guide vanes were built.
Zecan Tu +4 more
doaj +1 more source
The influence of non-equilibrium dissociation on the flow produced by shock impingement on a blunt body [PDF]
, 2004 We describe an investigation of the effects of non-equilibrium thermochemistry on the interaction between a weak oblique shock and the strong bow shock formed by a blunt body in hypersonic flow.
Hornung, H. G. +2 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Flow boiling with enhancement devices for cold plate coolant channel design [PDF]
The effects of enhancement devices on flow boiling heat transfer in circular coolant channels, which are heated over a fraction of their perimeters, are studied.
Boyd, Ronald D. +2 more
core +4 more sources
Case Studies in Thermal Engineering, 2021 Nanofluid as heat transfer medium in microchannel heat sink is very common. It is a promising approach to employ electrohydrodynamic(EHD) effect to improve the heat transfer efficiency.
Ruijin Wang +5 more
doaj +1 more source
Numerical investigation of pyrolysis effects on heat transfer characteristics and flow resistance of n-decane under supercritical pressure [PDF]
, 2018 This is an open access article distributed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International license (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/Pyrolysis of hydrocarbon fuel plays an important role ...
Hu, Xizhuo +3 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Phase Distribution of Gas–Liquid Slug–Annular Flow in Horizontal Parallel Micro-Channels
EnergiesAs a transitional flow pattern, slug–annular flow occurs over a wide range of operating conditions in micro-channels while its distribution in parallel micro-channels has not been well characterized.
Yanchu Liu +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source