Results 41 to 50 of about 929,788 (310)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Journal of Hebei University of Science and Technology, 2019 In order to enhance the heat transfer performance of CO2 heat pump, the heat transfer performance of supercritical carbon dioxide in horizontal straight tube is conducted based on Fluent numerical simulation method. Cooling heat transfer of supercritical
Haiting CUI, Siwen LIU, Shaozheng WANG
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Entropy, 2015 Performance tests were carried out for a microchannel printed circuit heat exchanger (PCHE), which was fabricated with micro photo-etching and diffusion bonding technologies.
Jang-Won Seo +4 more
doaj +1 more source
Entry aerodynamics and heating [PDF]
, 1974 An overview of the problems of entry aerodynamics and heating is given with emphasis on survival of the probe, predictability of performance, and reliability of performance.
Olstad, W.
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Zhileng xuebao, 2022 A performance test system for an evaporative condenser was developed in this study. The effects of different parameters on the heat transfer performance of an annular elliptic finned tube evaporative condenser were studied using a control variable method,
Gu Yaxiu +4 more
doaj
Thermal analysis and optimization of a heat regenerator composed of two coupled moving bed heat exchangers [PDF]
, 2008 This work presents a study to optimize the performance of a heat regenerator composed by two coupled moving bed heat exchangers (MBHE). A MBHE is used to recover heat, from a hot gas stream, and the other one is used to preheat an air stream.
Almendros Ibáñez, José Antonio +3 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source