Results 61 to 70 of about 157,809 (262)
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Experimental Comparison of R245fa Falling Film Evaporation in Two Doubly-enhanced Tubes
Zhileng xuebao, 2019 The heat transfer performance of two types of doubly enhanced tubes was experimentally studied using R245fa after the horizontal single-tube falling film evaporating test bench was built.
Zhao Jiapu +3 more
doaj
Flow and heat transfer characteristics of microchannel with grooves structure on sidewalls
河南理工大学学报. 自然科学版ObjectivesIn order to explore the effects of grooves shape on the liquid flow and heat transfer performances in microchannel heat sink（MCHS）， find an optimal groove geometry that can provide an efficient cooling performance with heat transfer enhancement
ZHU Qifeng +5 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Zhileng xuebao, 2012 Heat exchangers including condenser and evaporator are important equipments in the compression type refrigeration and air conditioning units, and their heat transfer coefficients have a direct effect on the efficiency and cost of the units.
Zhang Zhengguo +4 more
doaj
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The Effect of Heat Transfer on Turbine Performance
, 2020 Despite the blades downstream of the combustor being cooled in most large gas turbines, the effect this cooling has on their performance is still unclear. Fundamental questions, such as how turbine efficiency should be defined and which flow features reduce performance, remain unanswered. This thesis answers these questions and addresses the problem of
openaire +2 more sources
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source