Results 91 to 100 of about 418,548 (318)

Exergy optimization in a steady moving bed heat exchanger [PDF]

, 2007
Proceedings of: Interdisciplinary Transport Phenomena V: Fluid, Thermal, Biological, Materials and Space Sciences (ITP 2007), 14-19 of October, 2007, Bansko, Bulgaria (Oral paper nº 70)This work provides an exergy analysis of a moving bed heat exchanger
Soria Verdugo, Antonio, Ruiz-Rivas, Ulpiano, Soria-Verdugo, Antonio, Almendros Ibáñez, José Antonio, Ruiz-Rivas Hernando, Ulpiano, Almendros-Ibáñez, José Antonio, Santana Santana, Domingo José   +6 more
core  

Investigation Perspectives of Dynamics of Tank Vehicles for Liquid Loads

Механика машин, механизмов и материалов, 2007
It is analysed a current state and investigation perspectives of dynamics truck and rail tank vehicles. There are resulted equations presenting movement of considered system members.
A.O. Shimanovsky, Yu.M. Pleskachevsky, M.S. Vysotsky   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Thermal performance of an innovative heat sink using metallic foams and aluminum nanoparticles-Experimental study

, 2015
This paper presents an experimental investigation of thermal performance for four types of heat sinks. The investigated heat sinks were: extruded uncoated longitudinal fin heat sink, extruded coated longitudinal fin heat sink by aluminum nanoparticles ...
Lotfizadeh, Hossein, Rezazadeh, Sajjad, Mehrizi, Abbasali Abouei, Motlagh, Majid Sanagoo   +3 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

DEVELOPMENT OF TECHNOLOGY FOR APPLICATION OF PLASMA COMPOSITE COATINGS BASED ON ZIRCONIUM DIOXIDE FOR SPACECRAFT SYSTEMS

Наука и техника, 2015
The paper presents investigation results pertaining to the influence of such parameters as plasma jet (current, spraying distance, expenditure of plasma-forming gas – nitrogen), fraction composition of an initial powder and cooling rate with compressed ...
F. I., Panteleenko, V. A. Okovity, O. G. Devoino, V. M. Astashinsky, V. V. Okovity, S. В. Sobolewski   +5 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Aluminium Foams For Heat transfer Applications [PDF]

, 2012
Open cell metal foams show great potential as a heat exchangers, due to their permeability to fluids and the high conductivity of the metallic network.
Zaragoza, Gael
core  

A fundamental study on the heat transport characteristics in a pulsating heat pipe by using a forced oscillation system (Measurement of effective thermal conductivity)

Nihon Kikai Gakkai ronbunshu, 2015
Recently, highly efficient small heat transport devices have been required. In particular, pulsating heat pipes (PHP) have come to draw a lot of attention. The contribution of sensible heat transport and latent heat transport in oscillating working fluid,
Masayoshi MIURA, Takao NAGASAKI, Yutaka ITO   +2 more
doaj   +1 more source