Results 41 to 50 of about 14,701,351 (357)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Research progress on SiMOC coatings prepared by polymer pyrolysis and chemical vapor deposition

Heat Treatment and Surface Engineering, 2023
The SiOC materials have shown great potential for a number of engineering applications owing to their excellent physical and chemical properties. Due to the unique microstructure of SiOC coatings, different variants of polymer pyrolysis and chemical ...
Weichen Jing, Naeem ul Haq Tariq, Mingqiang Tang   +2 more
doaj   +1 more source

Laser Powder Bed Fusion of Inconel 718: Residual Stress Analysis Before and After Heat Treatment

, 2019
Residual stresses (RS) of great magnitude are usually present in parts produced by Laser Powder Bed Fusion (PBF-LB), mainly owing to the extreme temperature gradients and high cooling rates involved in the process.
R. Barros, Francisco J. G. Silva, R. Gouveia, A. Saboori, G. Marchese, S. Biamino, A. Salmi, E. Atzeni   +7 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

The Effect of Long-Term Aging on the Mechanical Properties of Corrosion-Resistant Nickel-Based Alloys for Their Application in Nuclear Technologies

Applied Sciences
The short-term mechanical properties of commercial corrosion-resistant nickel alloys based on Ni-Cr (Hastelloy® G-35® or UNS N06035), Ni-Mo (Hastelloy® B-3® or UNS N10675), and Ni-Cr-Mo (VDM® Alloy C-4 or UNS N06455, VDM® Alloy 59 or UNS N06059, and ...
Alfiya F. Gibadullina, Vladislav A. Khotinov, Maxim S. Karabanalov, Ilya B. Polovov   +3 more
doaj   +1 more source

Evidence of metal–organic coordination between Fe and flavonoid chrysin in a green anticorrosion film

Heat Treatment and Surface Engineering, 2022
This work shows interesting results for a metal–organic complex as a green corrosion inhibitor. The study describes features of two passive films (PF) containing chrysin for mild steel in H2SO4 by means of electrochemical noise under a potentiostaic ...
María Yesenia Díaz-Cárdenas, Jorge Uruchurtu Chavarín, María Guadalupe Valladares Cisneros, Selene Lagunas-Rivera, Elsa Carmina Menchaca Campos   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Improving the Cleanness of Low-Carbon Tube Steel Under Steel Plant Conditions

Advances in Materials Science and Engineering
Reducing the number of nonmetallic inclusions in high-quality steel rolled products is of great importance for all steel plants. One of the ways to decrease the size and quantity of alumina and silicate nonmetallic inclusions could be suppressing their ...
Dmytro Zotov, Kostiantyn Niziaiev, Oleg Uzlov, Oleksandr Puchykov   +3 more
doaj   +1 more source

Structure and mechanical properties of MAO coatings formed on aluminum-coated titanium alloy

Heat Treatment and Surface Engineering, 2022
Application of titanium alloys is restricted due to their low hardness and poor wear resistance. Duplex surface treatment consisting of depositing of Al coating by arc ion plating (AIP) plus micro-arc oxidation (MAO) was carried out on Ti6Al4V alloy to ...
Wei Zhang, Li Xin, Ying Fu, Zhong Han, Zhixiong Chen, Changjie Feng, Shenglong Zhu, Fuhui Wang   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source