Results 71 to 80 of about 1,365,131 (300)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
International Journal of Bio-Resource and Stress Management, 2023 The field experiments were carried out during rabi seasons of 2013−14 and 2014−15 at Research Farm, School of Climate Change and Agricultural Meteorology, PAU, Ludhiana to study the effect of different temperature regimes, nitrogen levels and post ...
Sukhjeet Kaur +2 more
doaj
Efficiency of use of waste heat energy on the example of Chelyabinsk [PDF]
E3S Web of Conferences, 2019 We consider the possibility of improving the existing heat-suppling system in Chelyabinsk through the introduction of heat pump technology for the disposal of waste low-grade heat.
Tseyzer Grigoriy +2 more
doaj +1 more source
Ca_3AlSb_3: an inexpensive, non-toxic thermoelectric material for waste heat recovery [PDF]
, 2011 Thermoelectric materials directly convert thermal energy into electrical energy, offering a promising solid-state solution for waste heat recovery.
Flage-Larsen, Espen +4 more
core
Improved Heat Demand Prediction of Individual Households [PDF]
, 2010 One of the options to increase the energy efficiency of current electricity network is the use of a Virtual Power Plant. By using multiple small (micro)generators distributed over the country, electricity can be produced more efficiently since these ...
Bakker, Vincent +4 more
core +3 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Agro-meteorological indices in relation to cotton yield in a Mediterranean environment
Notulae Scientia BiologicaeThe effect of climate change is an important factor that significantly affects flower and boll production and consequently cotton yield. Field experiment as conducted to study the effect of weather parameters on cotton yield and yield components under ...
Vassilis ENGONOPOULOS +3 more
doaj +1 more source
Geometric phaselike effects in a quantum heat engine
, 2017 By periodically driving the temperatures of reservoirs in quantum heat engines, geometric phase or Pancharatnam-Berry phase-like (PBp) effects in the thermodynamics can be observed.
Giri, Sajal Kumar +1 more
core +1 more source
Enhanced ELF wave generation efficiency using ‘O' mode HF heating
Geophysical Research Letters, 1997 We present here signals received near the Tromsø ionospheric heater facility when the heater was modulated with a 505Hz square wave. We found that whereas the harmonics of the square wave (≥ 1515 Hz) showed the accepted behaviour of reduced wave excitation on switching from ‘X' to ‘O' mode HF heating, the fundamental frequency showed enhanced ...
Barr, R. +3 more
openaire +2 more sources