Results 151 to 160 of about 992,907 (313)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Influence of temperature and time factors on ladle inoculation effect of cast iron

open access: yesЛитьë и металлургия, 2001
Influence of temperature and time factors on ladle inoculation effect of cast iron is investigated. It is shown that stability of inoculation effect in conditions of continuous soak is interrelated with activity of nucleating centres and character of ...
L. Z. Pisarenko
doaj  

Natural convection heating of liquids, with reference to sterilization of canned food

open access: yes, 1975
In a model system the physical transport phenomena that occur during the sterilization of a canned liquid food were investigated. Flow phenomena and heat transfer were studied experimentally as well as theoretically.
Hiddink, J.
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Counter modification of hypereutectic gray cast iron

open access: yesЛитьë и металлургия, 2001
Possibility of use of complex modification of hypereutectic gray cast iron by graphitizing and antigraphitizing additions for manufacture of castings with high antifriction and antiscratching properties is shown.
L. Z. Pisarenko
doaj  

Heat Exhaustion and Heat Stroke [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1964
openaire   +2 more sources

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Advanced technologies for foundry shops

open access: yesЛитьë и металлургия, 2000
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Yu. P. Bobrov
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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