Results 151 to 160 of about 2,557,464 (355)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
IMPLEMENTATION OF NEW TECHNOLOGIES AND EQUIPMENT TILL 2010 AT GAG “MINSK WORKS OF HEATING EQUIPMENT”
Литьë и металлургия, 2006 The brief perspective of implantation of new production of heating equipment till the year 2010 at ОАО *'MZOO'' is given.
S. F. Lukashevich
doaj
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
INTERNATIONAL SCIENTIFIC AND TECHNICAL CONFERENCE OF FOUNDERS AND METALLURGISTS
Литьë и металлургия, 2004 Information about the International Scientific Conference in Minsk on May 19—21 2004 and Celebration of 50-th Anniversary of Cathedra "Machine and Foundry Production"
Ju. P. Bobrov
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
RECONSTRUCTION OF THE ANNEALED AND GRAY CAST IRON WORKSHOP AT GAG “MZGG”
Литьë и металлургия, 2005 The advantages of moulding system DISA 230F (Denmark) are given. It is shown that enterprise gets economic effect from reduction of net cost of 1 tone casting of annealed and gray cast iron.
V. A. Vershinin
doaj