Results 11 to 20 of about 613,599 (267)

The heat is on [PDF]

open access: yesClimacteric, 2020
Three years ago, we wrote an editorial calling for more research on the use of vaginal lasers in gynecology before widespread adoption took hold1. Since then, there has been a varied response.
Hillard T. C., Nappi R. E.
openaire   +3 more sources

The Heat Is On …︁ [PDF]

open access: yesAngewandte Chemie International Edition, 2006
It is common knowledge that atherosclerosis is a multifactorial disease, and the disease-promoting role of classic risk factors for atherosclerosis, such as high serum cholesterol levels, diabetes, hypertension, smoking, and various types of infections, has been proven in innumerable clinical studies. Despite the fact that we are dealing with a chronic
openaire   +5 more sources

Gelling by Heating [PDF]

open access: yesScientific Reports, 2013
We introduce a simple model, a binary mixture of patchy particles, which has been designed to form a gel upon heating. Due to the specific nature of the particle interactions, notably the number and geometry of the patches as well as their interaction energies, the system is a fluid both at high and at low temperatures, whereas at intermediate ...
Roldan-Vargas, Sandalo   +3 more
openaire   +3 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Newton’s law of heating and the heat equation [PDF]

open access: yesInvolve, a Journal of Mathematics, 2009
Newton’s law of heating models the average temperature in an object by a simple ordinary differential equation, while the heat equation is a partial differential equation that models the temperature as a function of both space and time. A series solution of the heat equation, in the case of a spherical body, shows that Newton’s law gives an accurate ...
Gockenbach, Mark, Schmidtke, Kristin
openaire   +2 more sources

Modeling of Heat Flux in a Heating Furnace

open access: yesComputation, 2023
Modern heating furnaces use combined modes of heating the charge. At high heating temperatures, more radiation heating is used; at lower temperatures, more convection heating is used. In large heating furnaces, such as pusher furnaces, it is necessary to monitor the heating of the material zonally. Zonal heating allows the appropriate thermal regime to
Augustín Varga   +5 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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