Results 51 to 60 of about 992,907 (313)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

NEW PROGRAM OF THE BURDEN CALCULATION

Литьë и металлургия, 2004
In the article there is presented the universal computer program of calculation of burden for the different types of cast iron, smelted in cupolas and electric furnaces.
L. Z. Pisarenko, A. E. Shevchenko, F. S. Lukashevich, D. V. Kuis   +3 more
doaj  

The American Society of Heating and Ventilating Engineers Guide

, 1922
The purpose of the American Society of Heating and Ventilating Engineers Guide is to provide the engineer, the architect and the contractor alike, with a useful and reliable reference data book relating to the art of heating and ventilation. A wide range
American Society of Heating and Ventilating Engineers
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

International scientific and technical conference

Литьë и металлургия, 2003
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L. Z. Pisarenko, I. A. Potapnev
doaj  

The ‘District Heating Wall’:a synergistic approach to achieve affordable carbon emission reductions in old terraced houses

, 2012
One effective method to help the UK achieve GHG emission reduction targets is to reduce and decarbonise the heat demand of solid-walled terraced houses, as there are over 2.5 million such buildings making up a significant proportion of the whole building
Frost, Claire, MacGregor, Robert, Wang, Fan; id_orcid, Woods, Paul   +3 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

MECHANICAL REGENERATION OF SAND WASTE

Литьë и металлургия, 2005
The experimental activation of the sand regenerator of the firm SINTO is carried out at ОАО “MZOO". It is shown that sand grains are cleared from films of binding agents, that allows to use the treated sand for preparation of agglutinant and core sands.
D. I. Gnir, E. V. Govinchik
doaj  

Numerical Study on Peak Shaving Performance of Combined Heat and Power Unit Assisted by Heating Storage in Long-Distance Pipelines Scheduled by Particle Swarm Optimization Method

Energies
Thermal energy storage in long-distance heating supply pipelines can improve the peak shaving and frequency regulation capabilities of combined heat and power (CHP) units participating in the power grid.
Haoran Ju, Yongxue Wang, Yiwu Feng, Lijun Zheng   +3 more
doaj   +1 more source

An estimation of exergy consumption paterns of energy‐intensive building service systems

Journal of Civil Engineering and Management, 2006
This paper represents the estimation of life cycle exergy consumption for building service systems (BSS). The investigation explores public building engineering systems, which are the most energy‐intensive.
Darius BiekÅ¡a, Vytautas Martinaitis, Aloyzas Algimantas Å akmanas   +2 more
doaj   +1 more source