Results 61 to 70 of about 2,557,464 (355)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
NEW PROGRAM OF THE BURDEN CALCULATION
Литьë и металлургия, 2004 In the article there is presented the universal computer program of calculation of burden for the different types of cast iron, smelted in cupolas and electric furnaces.
L. Z. Pisarenko +3 more
doaj
, 2019 We present in this study the effects of short-term heating on organics in the Tagish Lake meteorite and how the difference in the heating conditions can modify the organic matter (OM) in a way that complicates the interpretation of a parent body’s ...
,, ,, Chan, Queenie H. S., Nakato, Aiko
core +1 more source
Observation of fast stochastic ion heating by drift waves [PDF]
, 1991 Anomalously fast ion heating has been observed in the Caltech Encore tokamak [Phys. Rev. Lett. 59, 1436 (1987)], with the use of laser-induced fluorescence.
Bellan, P. M. +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Литьë и металлургия, 2002 The aim of the article is to attract attention of founders to the problem of the cast iron heredity taking into account the latest achievements in this field.
L. Z. Pisarenko, S. F. Lukashevich
doaj
Tidal Heating of Extra-Solar Planets
, 2008 Extra-solar planets close to their host stars have likely undergone significant tidal evolution since the time of their formation. Tides probably dominated their orbital evolution once the dust and gas had cleared away, and as the orbits evolved there ...
Brian Jackson +5 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
EXPERIENCE OF THE PROCESS “THERMOSHOK” IMPLEMENTATION AT OA) “MZOO”
Литьë и металлургия, 2004 .
V. K. Filipchik, V. A. Hatskevich
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source