Results 61 to 70 of about 6,229,787 (282)

Spatiotemporal changes in the length and heating degree days of the heating period in Northeast China [PDF]

Meteorological Applications, 2017
ABSTRACTAs the coolest region in China, Northeast China has long and severe winters and is a main region for the use of central heating. Accurately predicting the heating energy consumption in Northeast China is very important for energy management and planning.
Xiang‐Jin Shen, Bin‐Hui Liu, Dao‐Wei Zhou   +2 more
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Canada - Heating Degree-Days

, 1981
Contained within the 5th Edition (1978 to 1995) of the National Atlas of Canada is a map that shows the annual sum of heating degree days (an indicator of building heating needs). Data for period 1941 to 1970. Companion sheet to Frost-Free Period, Growing Degree-Days, Last Frost in Spring and First Frost in Autumn.
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Inter-annual variability in fossil-fuel CO2 emissions due to temperature anomalies

Environmental Research Letters, 2017
It is well known that short-term (i.e. interannual) variations in fossil-fuel CO _2 emissions are closely related to the evolution of the national economies.
F-M Bréon, O Boucher, P Brender
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

WEATHER INDEX- THE BASIS OF WEATHER DERIVATIVES [PDF]

This paper approaches the subject of Weather Derivatives, more exactly their basic element the weather index. The weather index has two forms, the Heating Degree Day (HDD) and the Cooling Degree Day (CDD). We will try to explain their origin, use and the
Botos Horia Mircea, Ciumas Cristina
core  

Asymmetric Changes in Heating and Cooling Degree-Day Climates Across China in the Context of Faster Minimum-Temperature Warming

Atmosphere
Degree days are outdoor-temperature indicators relevant to heating and cooling. We compare land-area, fixed 2023 population raster, and fixed 2015 GDP raster summaries; no measures observed building energy use.
Ming Shang, Yanan Yao, Qian Li, Yihang Xing, Jingying Xu, Lei Bai   +5 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

[SUPERSEDED] Heating and cooling degree days projections for the UK: version 1

, 2016
[Dataset has been replaced by a newer version - http://datashare.is.ed.ac.uk/handle/10283/2813] This dataset was produced for the study "What is the uncertainty in degree day projections due to different calibration methodologies?" (Holmes et al ...
Holmes, Caroline
core   +1 more source