Results 131 to 140 of about 266,752 (314)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

An Advanced Thermal Decomposition Method to Produce Magnetic Nanoparticles with Ultrahigh Heating Efficiency for Systemic Magnetic Hyperthermia. [PDF]

Small Methods, 2022
Demessie AA, Park Y, Singh P, Moses AS, Korzun T, Sabei FY, Albarqi HA, Campos L, Wyatt CR, Farsad K, Dhagat P, Sun C, Taratula OR, Taratula O.   +13 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

ПОВЫШЕНИЕ ЭФФЕКТИВНОСТИ УПРАВЛЕНИЯ РЕЖИМАМИ ЭЛЕКТРИЧЕСКОГО ОБОГРЕВА ПРИ ПРЕССОВАНИИ ЗАГОТОВОК ПОДОВЫХ БЛОКОВ

Elektrotehnìka ta Elektroenergetika, 2008
Предложена методика оптимизации управления электрическим обогревом при прессовании заготовок подовых блоков.
D. S. Yarymbash, A. V. Tyutyunnik, O. L. Zagrunny   +2 more
doaj  

Self-Heating Flower-like Nanoconstructs with Limited Incorporation of Yttrium in Maghemite: Effect of Chemical Composition on Heating Efficiency, Cytotoxicity and Genotoxicity. [PDF]

Nanomaterials (Basel), 2023
Ognjanović M, Jaćimović Ž, Kosović-Perutović M, Besu Žižak I, Stanojković T, Žižak Ž, Dojčinović B, Stanković DM, Antić B.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Efficiency Determination of Latvian District Heating Plants [PDF]

This paper is dedicated for Latvian town and rural district heating system heat rate analysis. Developed methodology allows identifying indicators that influence heat tariff values and sets the benchmark values depending on the share of different fuels ...
Ziemele, Jeļena, Blumberga, Dagnija
core  

Impact of solar-driven heating strategies on the phase change thermal storage performance of erythritol

Frontiers in Chemistry
With escalating energy demands, solar power stands out for its abundance and renewable advantages, presenting a paramount sustainable solution. Herein, we tactically incorporate phase change material (PCM) into solar energy systems, resulting in ...
Yuxuan Deng, Yu Zhen, Xiaojuan Zhu, Yanna Li, Jing Xu   +4 more
doaj   +1 more source

Targeted Nanoparticles with High Heating Efficiency for the Treatment of Endometriosis with Systemically Delivered Magnetic Hyperthermia. [PDF]

Small, 2022
Park Y, Demessie AA, Luo A, Taratula OR, Moses AS, Do P, Campos L, Jahangiri Y, Wyatt CR, Albarqi HA, Farsad K, Slayden OD, Taratula O.   +12 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source