Results 161 to 170 of about 266,752 (314)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

An analysis of the feasibility of using a solar water heating system in a hotel : a case study [PDF]

open access: yes, 2010
Includes bibliographical references (p. 53-57).The use of solar energy to heat water will not only contribute to the mitigation of global climate change due to the reduced combustion of fossil fuels, but it will also reduce the demand on South Africa's ...
Fahy, Gary
core  

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

Efficiency Level of Centrifugal Pumps of Various Designs for Public Water Supply and District Heating Systems [PDF]

open access: yes
The goal of the research is to compare the efficiency level of centrifugal pumps of various designs to be used at the second stage pumping stations of public water supply systems and at the main pumping stations of district heating systems.
Dzelzītis, Egīls   +1 more
core  

Countering rising heating costs [PDF]

open access: yes, 2006
Title from caption of PDF document (viewed Mar.

core  

Rational Efficiency of a Heat Exchanger [PDF]

open access: yes, 2011
The authors propose a new and unique definition for the rational efficiency of a heat exchanger. This new rational efficiency is defined in terms of its sub-rational efficiencies: a heat transfer rational efficiency and a friction rational efficiency for each of the fluid systems comprising the heat exchanger.
McGovern, Jim, Smyth, Brian P.
openaire  

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