Results 41 to 50 of about 8,688,943 (304)

Earth's surface heat flux [PDF]

Solid Earth, 2009
Abstract. We present a revised estimate of Earth's surface heat flux that is based upon a heat flow data-set with 38 347 measurements, which is 55% more than used in previous estimates. Our methodology, like others, accounts for hydrothermal circulation in young oceanic crust by utilising a half-space cooling approximation.
Davies, J, Davies, Rhodri
openaire   +4 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Modeling of skin tissue heating using the generalized dual phase-lag equation

Archives of Mechanics, 2015
This paper concerns the numerical modeling of skin tissue heating. To describe the analyzed process the system of three generalized dual phase-lag equations corresponding to the successive layers of the skin: epidermis, dermis and sub-cutaneous region is
E. Majchrzak, Ł. Turchan, J. Dziatkiewicz   +2 more
doaj   +1 more source

Heating influence on hierarchical structures fabricated by direct laser interference patterning

Scientific Reports, 2022
The combination of direct laser interference patterning (DLIP) with laser-induced periodic surface structures (LIPSS) enables the fabrication of functional surfaces reported for a wide spectrum of materials. The process throughput is usually increased by
Nikolai Schröder, Fabian Nyenhuis, Robert Baumann, Lucinda Mulko, Thomas Kiedrowski, Johannes Albert L’huillier, Andrés Fabián Lasagni   +6 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

ЕКСПЕРИМЕНТАЛЬНІ ТА ЧИСЕЛЬНІ ДОСЛІДЖЕННЯ ТЕПЛОВІДДАЧІ ЗІ СКЛОПАКЕТА З ЕЛЕКТРОНАГРІВОМ ЙОГО ПОВЕРХНІ

Праці Інституту електродинаміки Національної академії наук України, 2022
The results of experimental and theoretical studies of heat transfer processes through a two-chamber double-glazed window (4i-10-4M1-10-4i) with electric heating are presented.
Б.І. Басок, Б.В. Давиденко, С.М. Гончарук, А.М. Павленко   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Climate-adaptive building envelopes: Benchmarking thermochromic coatings against static cool surfaces under future warming and occupancy scenarios

Case Studies in Thermal Engineering
Buildings use energy for cooling and heating to maintain indoor thermal comfort. Owing to rising temperatures and climate change, future energy demand for space cooling is expected to increase, whereas space heating requirements in winter may decline ...
Mansour Alhazmi
doaj   +1 more source

Solar repowering existing steam cycle power plants

International Journal of Thermofluids, 2023
Currently concentrating solar power technologies are increasingly being researched. Using solar energy for replacement of regenerative feed water heaters and partial replacement of economizer and evaporating heating surfaces of the existing steam ...
Erkinjon Matjanov, Zarina Akhrorkhujaeva
doaj   +1 more source