Results 41 to 50 of about 541,531 (303)

Effects of electrode surface roughness on motional heating of trapped ions [PDF]

open access: yes, 2016
Electric field noise is a major source of motional heating in trapped ion quantum computation. While the influence of trap electrode geometries on electric field noise has been studied in patch potential and surface adsorbate models, only smooth surfaces
Chuang, Issac L.   +2 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Study of high altitude plume impingement [PDF]

open access: yes, 1972
Computer program has been developed as analytical tool to predict severity of effects of exhaust of rocket engines on adjacent spacecraft surfaces. Program computes forces, moments, pressures, and heating rates on surfaces immersed in or subjected to ...
Greenwood, T. F.   +4 more
core   +1 more source

Orbital Deflection of Comets by Directed Energy [PDF]

open access: yes, 2019
Cometary impacts pose a long-term hazard to life on Earth. Impact mitigation techniques have been studied extensively, but they tend to focus on asteroid diversion.
Hughes, Gary B.   +2 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Numerical Simulation of Pool Boiling on Novel Microstructured Heated Surface

open access: yesEnergies
Improving the pool boiling heat transfer by changing the properties of the heating surface has been experimentally studied by many researchers. In this paper, two novel microstructured surfaces with open channels were simulated and investigated.
Chen Xu   +4 more
doaj   +1 more source

Analyses of Urban Pavement Surface Temperatures

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2015
Heat islands are areas that have higher air temperatures than their surroundings. It has been proven that the use of certain types of pavement surface materials contributes to the occurrence of heat islands.
Aleksandra Deluka-Tibljaš   +3 more
doaj   +1 more source

Insensitivity of Ion Motional Heating Rate to Trap Material over a Large Temperature Range

open access: yes, 2013
We present measurements of trapped-ion motional-state heating rates in niobium and gold surface-electrode ion traps over a range of trap-electrode temperatures from approximately 4 K to room temperature (295 K) in a single apparatus.
Chiaverini, J., Sage, J. M.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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