Results 81 to 90 of about 536,274 (288)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Loose volume model research on the interference fit compressor rotor using the method of temperature difference

Journal of Hebei University of Science and Technology, 2015
In order to dismantle non-destructively the impeller and shaft under interference fit, the loaded temperature is planned reasonably for the temperature difference dismantling process.
Jian SHEN, Weizhen YANG, Dan ZHOU, Guangfu LIU, Xiaodong DU   +4 more
doaj   +1 more source

Influence of monolayer contamination on electric-field-noise heating in ion traps

, 2012
Electric field noise is a hinderance to the assembly of large scale quantum computers based on entangled trapped ions. Apart from ubiquitous technical noise sources, experimental studies of trapped ion heating have revealed additional limiting ...
Kim, E., Rabl, P., Sadeghpour, H. R., Safavi-Naini, A., Weck, P. F.   +4 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Biofilm on total joint replacement materials can be reduced through electromagnetic induction heating using a portable device

Journal of Orthopaedic Surgery and Research
Background Periprosthetic joint infection is a serious complication following joint replacement. The development of bacterial biofilms bestows antibiotic resistance and restricts treatment via implant retention surgery.
Cordero García-Galán Enrique, Marina Medel-Plaza, John Jairo Aguilera Correa, Héctor Sarnago, Jesús Acero, José M. Burdio, Óscar Lucía, Jaime Esteban, Enrique Gómez-Barrena   +8 more
doaj   +1 more source

Convective Heating of Solid Surface: Entropy Generation Due to Temperature Field and Thermal Displacement

Entropy, 2003
: Convective heating and cooling of the surfaces find application in process industry. During the heating or cooling cycle of the process, thermodynamic irreversibility which can be associated with the process parameters occurs.
Yagoub Nassar Al-Nassar
doaj   +1 more source

Continuous fiber thermoplastic prepreg [PDF]

, 1993
A pultrusion machine employing a corrugated impregnator vessel to immerse multiple, continuous strand, fiber tow in an impregnating material, and an adjustable metered exit orifice for the impregnator vessel to control the quantity of impregnating ...
Johnson, Gary S., Wilson, Maywood L.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Surface Temperature and Surface Heat Flux Determination of the Inverse Heat

Bulletin of JSME, 1986
A method for determining the surface temperature and surface heat flux of a one-dimensional solid, is developed by integration of Duhamel's integral which includes unknown temperature or unknown heat flux in its integrand. Specific forms of surface condition determination are devloped for sample inverse problems : slab, hollow cylinder, cylinder ...
openaire   +2 more sources