Results 71 to 80 of about 541,531 (303)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Structural solutions impact on thermal energy efficiency of heating surface at an open space

Journal of Civil Engineering and Management, 2013
This paper presents studies on thermal energy efficiency of heating surface at an open space according to structural solutions and climatic conditions. Numerical simulation research was conducted to assess three different types of heating surfaces at an ...
Dobrosława Kaczorek, Halina Koczyk
doaj   +1 more source

Comparison of software models for energy savings from cool roofs [PDF]

, 2016
A web-based Roof Savings Calculator (RSC) has been deployed for the United States Department of Energy as an industry-consensus tool to help building owners, manufacturers, distributors, contractors and researchers easily run complex roof and attic ...
Huang, Y, Levinson, R, Miller, WA, New, J   +3 more
core   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Experimental investigation of abrasive potential and drilling efficiency at elevated temperatures via Cerchar rock scratching

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
To see if and how abrasive potential as well as drilling efficiency change due to rock heating, Cerchar scratch tests were performed on six types of rock at eight temperature levels. Results indicate that rock abrasivity is temperature-dependent.
Guangzhe Zhang, Heinz Konietzky, Thomas Frühwirt   +2 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Continuous fiber thermoplastic prepreg [PDF]

, 1993
A pultrusion machine employing a corrugated impregnator vessel to immerse multiple, continuous strand, fiber tow in an impregnating material, and an adjustable metered exit orifice for the impregnator vessel to control the quantity of impregnating ...
Johnson, Gary S., Wilson, Maywood L.
core   +1 more source

Multi-ion sensing of dipolar noise sources in ion traps

, 2017
Trapped-ion quantum platforms are subject to `anomalous' heating due to interactions with electric-field noise sources of nature not yet completely known.
Alonso, J., Galve, F., Zambrini, R.
core   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Impact of Elevated Wall Temperatures on Nitrate Salt Stability in Thermal Energy Storage

Energies
Energy storage is vital for on-demand electricity generation from renewable sources like wind and solar. Besides employing batteries, retrofitting conventional fossil-fired power plants with thermal energy storage might present a highly cost-effective ...
Freerk Klasing, Thomas Bauer
doaj   +1 more source