Results 81 to 90 of about 541,531 (303)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Forced heat loss from body surface reduces heat flow to body surface [PDF]

open access: yesJournal of Dairy Science, 2010
Heat stress is commonly relieved by forced evaporation from body surfaces. The mode of heat stress relief by heat extraction from the periphery is not clear, although it reduces rectal temperature. Radiant surface temperature (Ts) of the right half of the body surface was examined by thermovision in 4 lactating Holstein cows (30 kg of milk/d) during 7 ...
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Heat Transfer in a Scraped Surface Heat Exchanger

open access: yesNIPPON SHOKUHIN KOGYO GAKKAISHI, 1987
Heat transfer in a pilot scale scraped surface heat exchanger was experimentally investigated, using water and gelatinized wheat flour fluids (solid content 1.8-10.7% (w/w)) as working fluids. Because gelatinized wheat flour fluids had non-NEWTONIAN characteristics, apparent viscosity of the fluids in the scraped surface heat exchanger was determined ...
Haruyoshi YAMAMOTO   +3 more
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Cosmic-ray induced diffusion in interstellar ices

open access: yes, 2014
Cosmic rays are able to heat interstellar dust grains. This may enhance molecule mobility in icy mantles that have accumulated on the grains in dark cloud cores.
Kalvans, Juris
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Implications of surface noise for the motional coherence of trapped ions

open access: yes, 2016
Electric noise from metallic surfaces is a major obstacle towards quantum applications with trapped ions due to motional heating of the ions. Here, we discuss how the same noise source can also lead to pure dephasing of motional quantum states.
Daniilidis, N.   +7 more
core   +1 more source

Analyzing the Cutting Process of a Heated Flexible Blade in Extruded Polystyrene Foam [PDF]

open access: yes, 2004
For the “Free Form Thick Layered Object Manufacturing” technology that is being developed at the Delft University, it is vital that Extruded Polystyrene Foam (XPS) can be cut accurately with a heated blade. The shape of the blade is actively controlled
Broek, Han J., de Smit, Bram
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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