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Heatstroke-Induced Inflammatory Response and Therapeutic Biomarkers

Biomedicines
In recent years, heatstroke has become one of the most dangerous illnesses associated with hyperthermia. Hyperthermia is described as an increased body temperature, where there is more heat accrual than dissipation, which happens during environmental ...
Piyush Baindara, Santi M Mandal
exaly   +3 more sources

Investigating the Association Between Heatstroke Mortality and Climatic Factors in Bangladesh: An Ecological Time Series Study [PDF]

Health Science Reports
Background and Aims Heatstroke is a life‐threatening illness with increasing global prevalence, largely influenced by weather conditions. It is a major health concern in Bangladesh, where the climate is especially hot and humid during the summer months ...
Md. Mamun Miah, Farjana Haque Pingki, Sarmin Akhter, Mehedi Hasan, Minhaz Uddin, Rakib Rahman, Tanzir Ahamed Raihan, Md. Shiblur Rahaman   +7 more
doaj   +2 more sources

Gut microbiota-derived xanthohumol protects against heatstroke by inhibiting macrophage pyroptosis in mice

Journal of Advanced Research
Background: Heatstroke is a critical illness induced by heat stress, characterized by circulatory failure and multiple organ dysfunctions. Accumulating evidence suggests that the pathophysiology of various diseases is closely associated with the gut ...
Qiaobing Huang, Zhongqing Chen
exaly   +3 more sources

Influence of the coronavirus disease 2019 (COVID‐19) pandemic on the incidence of heat stroke and heat exhaustion in Japan: a nationwide observational study based on the Heatstroke STUDY 2019 (without COVID‐19) and 2020 (with COVID‐19)

Acute Medicine & Surgery, 2022
Aim To assess heat stroke and heat exhaustion occurrence and response during the coronavirus disease 2019 pandemic in Japan. Methods This retrospective, multicenter, registry‐based study describes and compares the characteristics of patients between the ...
Jun Kanda, Yasufumi Miyake, Tadashi Umehara, Shoichi Yoshiike, Motoki Fujita, Kei Hayashida, Toru Hifumi, Hitoshi Kaneko, Tatsuho Kobayashi, Yutaka Kondo, Takashi Moriya, Yohei Okada, Yuichi Okano, Junya Shimazaki, Shuhei Takauji, Junko Yamaguchi, Masaharu Yagi, Hiroyuki Yokota, Keiki Shimizu, Arino Yaguchi, Shoji Yokobori   +20 more
doaj   +1 more source

Accidental hypothermia: characteristics, outcomes, and prognostic factors—A nationwide observational study in Japan (Hypothermia study 2018 and 2019)

Acute Medicine & Surgery, 2021
Aim This study describes the clinical characteristics and outcomes as well as the prognostic factors of patients with accidental hypothermia (AH) using Japan’s nationwide registry data. Methods The Hypothermia study 2018 and 2019, which included patients
Shuhei Takauji, Toru Hifumi, Yasuaki Saijo, Shoji Yokobori, Jun Kanda, Yutaka Kondo, Kei Hayashida, Junya Shimazaki, Takashi Moriya, Masaharu Yagi, Junko Yamaguchi, Yohei Okada, Yuichi Okano, Hitoshi Kaneko, Tatsuho Kobayashi, Motoki Fujita, Keiki Shimizu, Hiroyuki Yokota   +17 more
doaj   +1 more source

External validation of 5A score model for predicting in-hospital mortality among the accidental hypothermia patients: JAAM-Hypothermia study 2018–2019 secondary analysis

Journal of Intensive Care, 2022
Background The 5A score including five components “Age, Activities of daily living, Arrest, Acidemia and Albumin” was developed as an easy-to-use screening tool for predicting in-hospital mortality among patients with accidental hypothermia. However, the
Yohei Okada, Tasuku Matsuyama, Kei Hayashida, Shuhei Takauji, Jun Kanda, Shoji Yokobori   +5 more
doaj   +1 more source

Association between frailty and mortality among patients with accidental hypothermia: a nationwide observational study in Japan

BMC Geriatrics, 2021
Background Frailty has been associated with a risk of adverse outcomes, and mortality in patients with various conditions. However, there have been few studies on whether or not frailty is associated with mortality in patients with accidental hypothermia
Shuhei Takauji, Toru Hifumi, Yasuaki Saijo, Shoji Yokobori, Jun Kanda, Yutaka Kondo, Kei Hayashida, Junya Shimazaki, Takashi Moriya, Masaharu Yagi, Junko Yamaguchi, Yohei Okada, Yuichi Okano, Hitoshi Kaneko, Tatsuho Kobayashi, Motoki Fujita, Keiki Shimizu, Hiroyuki Yokota, Arino Yaguchi   +18 more
doaj   +1 more source

Current status of active cooling, deep body temperature measurement, and face mask wearing in heat stroke and heat exhaustion patients in Japan: a nationwide observational study based on the Heatstroke STUDY 2020 and 2021

Acute Medicine & Surgery, 2023
Aim The study aimed to determine the current status of face mask use, deep body temperature measurement, and active cooling in patients suffering from heat stroke and heat exhaustion in Japan.
Jun Kanda, Yasufumi Miyake, Daiki Tanaka, Tadashi Umehara, Maiko Yamazaki, Naoshige Harada, Motoki Fujita, Kei Hayashida, Hitoshi Kaneko, Tatsuho Kobayashi, Yukari Miyoshi, Yuki Kishihara, Yohei Okada, Yuichi Okano, Jotaro Tachino, Shuhei Takauji, Junko Yamaguchi, Atsuo Maeda, Hiroyuki Yokota, Shoji Yokobori   +19 more
doaj   +1 more source

Difference between 5A score and the HOPE score

Journal of Intensive Care, 2022
Recently, a letter to the editor was published to comment on the 5A score which is the prediction model for accidental hypothermia patients comparing the HOPE score.
Yohei Okada, Tasuku Matsuyama, Kei Hayashida, Shuhei Takauji, Jun Kanda, Shoji Yokobori   +5 more
doaj   +1 more source

Heatstroke-induced late-onset neurological deficits in mice caused by white matter demyelination, Purkinje cell degeneration, and synaptic impairment in the cerebellum

Scientific Reports, 2022
Global warming increases heatstroke incidence. After heatstroke, patients exhibit neurological symptoms, suggesting cerebellar damage. However, the potential long-term adverse outcomes are poorly understood.
Kazuyuki Miyamoto, Motoyasu Nakamura, Hirokazu Ohtaki, Keisuke Suzuki, Hiroki Yamaga, Kaoru Yanagisawa, Atsuo Maeda, Masaharu Yagi, Munetaka Hayashi, Kazuho Honda, Kenji Dohi   +10 more
doaj   +1 more source