PROTEOMICS, EarlyView.ABSTRACT Despite their widespread use as a research model, a comprehensive, quantitative proteomic profile of the cultured hippocampal neurons has remained unexplored. Here, we provide the first global proteomic characterization of primary murine hippocampal neurons cultured for 14 days under near‐physiological glucose conditions (2.5 mM).
Dominika Drulis‐Fajdasz +6 more
wiley +1 more source
Unveiling a flip-over retention mechanism in the gas-phase Cl<sup>-</sup> + (CH<sub>3</sub>)<sub>3</sub>CI S<sub>N</sub>2 reaction. [PDF]
Nat CommunLu X +8 more
europepmc +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Stepped collisional energy improves protein acylation identification by eliminating positional bias of cyclic immonium ions. [PDF]
Commun ChemZhu ZY, Mao PZ, Tarn C, Cao Y.
europepmc +1 more source
Quality and Reliability Engineering International, EarlyView.ABSTRACT Corrosion remains a critical threat to the integrity and service life of infrastructure in industries such as oil, gas, construction, renewable energy, and transportation. Traditional inspection methods, being labor‐intensive, hazardous, and often subjective, fall short in addressing modern inspection demands.
Alhossein Alharbi +3 more
wiley +1 more source
Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement
Geophysical Monograph Series, Page 27-82., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm +2 more
wiley +1 more source
Native-Like Protein Structures in Vacuo: Steric Cooperativity as a Kinetic Barrier to Denaturation. [PDF]
JACS AuBleiholder C, Pedrete T, Lee J, Liu FC.
europepmc +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale Recent advances in high‐throughput molecular analyses of collagen peptides, especially ZooMS (Zooarchaeology by Mass Spectrometry), have permitted breakthroughs in the analysis of archaeological material that is highly fragmented, a factor that hinders morphological identification.
Pauline Raymond +8 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler +7 more
wiley +1 more source
Irradiation-Induced Defect Engineering in REBCO Coated Conductors: Mechanisms, Effects, and Perspectives. [PDF]
Materials (Basel)Li Y +6 more
europepmc +1 more source