Results 41 to 50 of about 41,863 (267)
A Student’s t Mixture Probability Hypothesis Density Filter for Multi-Target Tracking with Outliers
Sensors, 2018 In multi-target tracking, the outliers-corrupted process and measurement noises can reduce the performance of the probability hypothesis density (PHD) filter severely.
Zhuowei Liu +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Heavy-Tailed Gleser Model: Properties, Estimation, and Applications
Mathematics, 2022 In actuarial statistics, distributions with heavy tails are of great interest to actuaries, as they represent a better description of risk exposure through a type of indicator with a certain probability.
Neveka M. Olmos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Asymptotics for the Solutions to Defective Renewal Equations
Abstract and Applied Analysis, 2014 This paper investigates the defective renewal equations under the nonconvolution equivalent distribution class. The asymptotics of the solution to the defective renewal equations have been given for the heavy-tailed and light-tailed cases, respectively.
Kaiyong Wang, Yang Chen, Zhongquan Tan
doaj +1 more source
Mathematics, 2023 This paper discusses the problem of the mean changes in time series with heavy-tailed AR(p) noise. Firstly, it proposes a modified ratio-type test statistic, and the results show that under the null hypothesis of no mean change, the asymptotic ...
Tianming Xu, Yuesong Wei
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Distributed Consensus Multi-Distribution Filter for Heavy-Tailed Noise
Journal of Sensor and Actuator NetworksDistributed state estimation is one of the critical technologies in the field of target tracking, where the process noise and measurement noise may have a heavy-tailed distribution.
Guan-Nan Chang +4 more
doaj +1 more source