Results 91 to 100 of about 1,130,735 (339)

Data to understand the biotransfer of heavy metals along the soil-plant-edible insect-human food chain in Africa

Data in Brief, 2023
Data on the biotransfer of heavy metals along the soil-plant-edible insect-human food chain collected along a 60km pollution gradient is presented here.
Susan Mwelwa, Donald Chungu, Frank Tailoka, Dennis Beesigamukama, Chrysantus M. Tanga   +4 more
doaj  

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Renormalized Fermi hypernetted chain approach in medium-heavy nuclei

, 2007
The application of the Correlated basis function theory and of the Fermi hypernetted chain technique, to the description of the ground state of medium-heavy nuclei is reviewed.
Bisconti, C., Co', G., de Saavedra, F. Arias, Fabrocini, A.   +3 more
core   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Further studies on an eleventh case of heavy (Hgamma1) chain disease--biosynthetic studies [PDF]

, 1975
In vitro quantitative biosynthetic studies were carried out on bone marrow cells obtained from an eleventh case with gamma heavy chain disease. The findings indicate that neither cytoplasmic nor extracellular degradation was responsible for the presence ...
Arima, Terukatsu, Hirohata, Mamoru, Imai, Masanobu, Kuwauchi, Satoshi, Miyamoto-Sudo, Chizuko, Tanigawa, Takashi, Tsuboi, Shuhei, Tsunajima, Takehiko   +7 more
core   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

Nature Communications, 2019
Multiple myeloma is frequently characterised by translocation of genes next to the immunoglobulin heavy chain locus. In this study, the authors sequence a large cohort of high risk myeloma samples and find translocations of cMyc to the immunoglobulin ...
Benjamin G. Barwick, Paola Neri, Nizar J. Bahlis, Ajay K. Nooka, Madhav V. Dhodapkar, David L. Jaye, Craig C. Hofmeister, Jonathan L. Kaufman, Vikas A. Gupta, Daniel Auclair, Jonathan J. Keats, Sagar Lonial, Paula M. Vertino, Lawrence H. Boise   +13 more
doaj   +1 more source

OPE for null Wilson loops and open spin chains

, 2012
Maximal helicity-violating scattering amplitudes in N=4 supersymmetric Yang-Mills theory are dual to Wilson loops on closed null polygons. We perform their operator product expansion analysis in two-dimensional kinematics in the soft-collinear ...
A.V. Belitsky, Alday, Alday, Alday, Anastasiou, Basso, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Bern, Bern, Brandhuber, Braun, Braun, Caron-Huot, Corrigan, Del Duca, Del Duca, Del Duca, Derkachov, Derkachov, Dixon, Drummond, Drummond, Drummond, Durand, Gaiotto, Gaiotto, Goncharov, Goncharov, Gubser, Heslop, Lipatov, Mason, Sever   +36 more
core   +1 more source

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice [PDF]

, 1994
We have examined the regulatory role of the individual components of the immunoglobulin antigen receptor in B-cell development by transgenic complementation of Rag-1 deficient (Rag-1⁻) mice. Complementation with a membrane µ heavy chain (µHC) gene allows
Baltimore, David, Corcoran, Lynn M., Hardy, Richard R., Nemazee, David, Nussenzweig, Michel C., Roman, Christopher A. J., Schlissel, Mark S., Shinton, Susan A., Silver, Daniel P., Spanopoulou, Eugenia   +9 more
core