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Design of embedded-hybrid antimicrobial peptides with enhanced cell selectivity and anti-biofilm activity. [PDF]

open access: yesPLoS ONE, 2014
Antimicrobial peptides have attracted considerable attention because of their broad-spectrum antimicrobial activity and their low prognostic to induce antibiotic resistance which is the most common source of failure in bacterial infection treatment along
Wei Xu   +4 more
doaj   +1 more source

Solution to peptide sequencing challenge [PDF]

open access: yesAnalytical and Bioanalytical Chemistry, 2013
The cyclic peptide described is kalata B1 [1, 2] and its structure is shown in Fig. 1. The partial reduction of the cyclic peptide [2, 3] allows one to establish the disulfide connectivity. The first peptide is amino-ethylated at only {2}Cys and {5}Cys, whereas the second peptide is amino-ethylated at only {1}Cys and {4}Cys.
openaire   +3 more sources

Identification and Characterization of a Hexapeptide with Activity Against Phytopathogenic Fungi That Cause Postharvest Decay in Fruits

open access: yesMolecular Plant-Microbe Interactions, 2000
A hexapeptide of amino acid sequence Ac-Arg-Lys-Thr-Trp-Phe-Trp-NH 2 was demonstrated to have antimicrobial activity against selected phytopathogenic fungi that cause postharvest decay in fruits.
Belén López-García   +3 more
doaj   +1 more source

Mass Analysis Peptide Sequence Prediction (MAPSP) [PDF]

open access: yesBioinformatics, 2006
Abstract Summary: The software tool MAPSP allows the combinatorial prediction of novel short peptides such as hormones with common sequence features. In addition, it assists in de novo sequencing in general. The tool was designed for use in conjunction with the analytical identification method of mass spectrometry (MS) and it can ...
Martin, Eisenacher   +2 more
openaire   +2 more sources

Exploring Protein-Peptide Binding Specificity through Computational Peptide Screening. [PDF]

open access: yesPLoS Computational Biology, 2013
The binding of short disordered peptide stretches to globular protein domains is important for a wide range of cellular processes, including signal transduction, protein transport, and immune response.
Arnab Bhattacherjee, Stefan Wallin
doaj   +1 more source

Peptide sequencing challenge

open access: yesAnalytical and Bioanalytical Chemistry, 2012
Challenge, a series of puzzles to entertain and challenge our readers. This special ABC feature has established itself as a truly unique quiz series, with a new scientific puzzle published every other month. Readers can access the complete collection of published problems with their solutions on the Analytical and Bioanalytical Chemistry homepage at ...
openaire   +4 more sources

LC provides peptide sequence information [PDF]

open access: yesAnalytical Chemistry, 2007
LC retention times can supplement information from MS.
openaire   +2 more sources

The first salamander defensin antimicrobial peptide. [PDF]

open access: yesPLoS ONE, 2013
Antimicrobial peptides have been widely identified from amphibian skins except salamanders. A novel antimicrobial peptide (CFBD) was isolated and characterized from skin secretions of the salamander, Cynops fudingensis.
Ping Meng   +5 more
doaj   +1 more source

Cloning Trap for Signal Peptide Sequences [PDF]

open access: yesBioTechniques, 2000
Novel secreted and/or type I transmembrane proteins containing N-terminal signal sequences have been successfully cloned using the signal sequence trapping (SST) method. Often this involves random cloning of short 5' cDNA terminal ends into an epitope-tagged expression vector and the detection of expressed recombinant proteins on the cell surfaces of ...
Lim SP, GARZINO DEMO, ALFREDO
openaire   +4 more sources

Antihyperuricemic activity and inhibition mechanism of xanthine oxidase inhibitory peptides derived from whey protein by virtual screening

open access: yesJournal of Dairy Science
: Xanthine oxidase (XO), a rate-limiting enzyme in uric acid production, is the pivotal therapeutic target for gout and hyperuricemia. In this study, 57 peptides from α-lactalbumin and β-lactoglobulin were obtained via virtual enzymatic hydrolysis, and ...
Yaru Xu, Han Gong, Yang Zou, Xueying Mao
doaj   +1 more source

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