Results 81 to 90 of about 398,844 (320)
Tail behaviour of stationary distribution for Markov chains with asymptotically zero drift [PDF]
arXiv, 2012 We consider a Markov chain on $R^+$ with asymptotically zero drift and finite second moments of jumps which is positive recurrent. A power-like asymptotic behaviour of the invariant tail distribution is proven; such a heavy-tailed invariant measure happens even if the jumps of the chain are bounded. Our analysis is based on test functions technique and
arxiv
On the stability of rotating heavy chains
Journal of Differential Equations, 1979 AbstractThe object of this paper is two-fold. On the one hand we want to develop the duality theory for critical points which is introduced in [4]. The main result in this context is that if two critical points are in duality, and one of them is a local minimiser of its functional, then so is the other.
openaire +2 more sources
Alpha heavy chain disease [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018 lpha heavy chain disease (HCD) is the most prevalent form of heavy chain diseases, a rare family of syndromes associated with or representing a B cell malignancy variant. The hallmark characteristic and the pathogenic mechanism of HCD is the synthesis of a mutant, misfolded immunoglobulin heavy chain (IgH) which cannot form a quaternary conformation ...
Bianchi, Giada, Anderson, Kenneth C
openaire +2 more sources
Mapping Hsp104 interactions using cross‐linking mass spectrometry
FEBS Open Bio, EarlyView.This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal +3 more
wiley +1 more source
Heavy Higgs as a Portal to the Supersymmetric Electroweak Sector [PDF]
, 2018 The electroweak sector of the Minimal Supersymmetric Standard Model (MSSM) - neutralinos, charginos and sleptons - remains relatively weakly constrained at the LHC due in part to the small production cross sections of these particles. In this paper, we study the prospects of searching for decays of heavy Higgs bosons into these superpartners at the ...
arxiv +1 more source
FEBS Open Bio, EarlyView.SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel +13 more
wiley +1 more source
Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis.
PLoS Genetics, 2019 The interplay between signalling pathways and metabolism is crucial for tissue growth. Yet, it remains poorly understood. Here, we studied the consequences of modulating iron metabolism on the growth of Drosophila imaginal discs.
Simone Mumbauer +3 more
doaj +1 more source
BMC Research Notes, 2010 Background Heavy chain phosphorylation plays a central role in regulating myosin II bipolar filament assembly in Dictyostelium, as well as in higher eukaryotic nonmuscle cells. Our previous work has demonstrated that the WD-repeat domain of Dictyostelium
Steimle Paul A +2 more
doaj +1 more source
Gaussian-Chain Filters for Heavy-Tailed Noise with Application to Detecting Big Buyers and Big Sellers in Stock Market [PDF]
arXiv, 2014 We propose a new heavy-tailed distribution --- Gaussian-Chain (GC) distribution, which is inspirited by the hierarchical structures prevailing in social organizations. We determine the mean, variance and kurtosis of the Gaussian-Chain distribution to show its heavy-tailed property, and compute the tail distribution table to give specific numbers ...
arxiv
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source