Results 201 to 210 of about 563,152 (335)

Molecular genetic identification of clonal rearranged immunoglobulin heavy chain genes and detection of minimal residual disease in aggressive B-cell Non-Hodgkin's lymphoma

, 2018
von Hofen, Matthias
openalex   +1 more source

Graft-versus-leukemia activity may overcome therapeutic resistance of chronic lymphocytic leukemia with unmutated immunoglobulin variable heavy-chain gene status: implications of minimal residual disease measurement with quantitative PCR [PDF]

, 2004
Matthias Ritgen, Stephan Stilgenbauer, Nils von Neuhoff, Andreas Humpe, Monika Brüggemann, Christiane Pott, Thorsten Raff, Alexander Kröber, Donald Bunjes, Richard F. Schlenk, Norbert Schmitz, Hartmut Döhner, Michael Kneba, Peter Dreger   +13 more
openalex   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Bortezomib plus dexamethasone for a complete remission of heavy chain deposition disease： one case report with a literature review

Linchuang shenzangbing zazhi, 2022
Cheng Ya-qi, He Kun, Zheng Xi-xi, Wen Yu-bing, Fan Xiao-hong, Li Ming-xi   +5 more
doaj  

Classical complement activation in light and heavy chain deposition disease with acquired cutis laxa and bronchiolitis obliterans: a case report of monoclonal gammopathy of clinical significance. [PDF]

Front Immunol
Chen Y, Fan Y, Yang S, Cui H, Ye W, Ye W, Wen Y, Zhuang J, Wang P, Ma D, Fang K, Xia P, Chen L, Li H, Li C.   +14 more
europepmc   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Mu heavy chain disease

, 2018
Giada Bianchi, Kenneth C. Anderson
openalex   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Shared molecular profiles of anti-PL12 autoantibodies in anti-synthetase syndrome. [PDF]

Rheumatology (Oxford)
Ali SB, Troelnikov A, Amour B, Hender L, Beroukas D, Chataway T, Limaye V, Gordon TP, Wang JJ.   +8 more
europepmc   +1 more source

Isolated Mu Heavy Chain Deposition Disease—A Rare Cause of Spontaneous Splenic Rupture in a Young Adult [PDF]

Swe Swe Hlaing, Gàbor Varadi, Arnold Bloom, Ellen D. McPhail, Rekha Bhat   +4 more
openalex   +1 more source