Results 281 to 290 of about 563,152 (335)
Cryo-EM structure of shutdown human non-muscle myosin 2A
Casas-Mao D, Carrington G, Peckham M.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Best Practice & Research Clinical Haematology, 2005
Heavy chain diseases (HCDs) are rare B-cell lymphoplasma-cell proliferative disorders characterized by production of truncated monoclonal immunoglobulin heavy chains without associated light chains. HCDs involving the three main immunoglobulin classes have been described; alpha-HCD is the most common and has the most uniform presentation, gamma- and mu-
Dietlind L, Wahner-Roedler +1 more
openaire +2 more sources
Heavy chain diseases (HCDs) are rare B-cell lymphoplasma-cell proliferative disorders characterized by production of truncated monoclonal immunoglobulin heavy chains without associated light chains. HCDs involving the three main immunoglobulin classes have been described; alpha-HCD is the most common and has the most uniform presentation, gamma- and mu-
Dietlind L, Wahner-Roedler +1 more
openaire +2 more sources
Hematology/Oncology Clinics of North America, 1999
This review underscores the diversity of the structural and genetic abnormalities of HCD proteins and of the clinicopathologic features of the underlying lymphoproliferative disorders. Cells producing HCD may, however, all derive from a common normal precursor, which could be a rare B cell in the process of immunoglobulin gene somatic mutation within ...
J P, Fermand, J C, Brouet
openaire +2 more sources
This review underscores the diversity of the structural and genetic abnormalities of HCD proteins and of the clinicopathologic features of the underlying lymphoproliferative disorders. Cells producing HCD may, however, all derive from a common normal precursor, which could be a rare B cell in the process of immunoglobulin gene somatic mutation within ...
J P, Fermand, J C, Brouet
openaire +2 more sources
Annals of the New York Academy of Sciences, 1971
The recent elucidation of the structure of immunoglobulins, and the more precise immunologic and chemical characterization of the proteins produced by patients with proliferative disorders of plasma cells and lymphocytes have led to a clearer understanding of the biosynthetic alterations accompanying them.
E C, Franklin, B, Frangione, S, Cooper
openaire +2 more sources
The recent elucidation of the structure of immunoglobulins, and the more precise immunologic and chemical characterization of the proteins produced by patients with proliferative disorders of plasma cells and lymphocytes have led to a clearer understanding of the biosynthetic alterations accompanying them.
E C, Franklin, B, Frangione, S, Cooper
openaire +2 more sources
Current Treatment Options in Oncology, 2002
The heavy chain diseases (HCDs) are rare B-cell malignancies that are distinguished by the production of a monoclonal immunoglobulin heavy chain (HC) without an associated light chain by the malignant B-cells. There are three types of HCD defined by the class of immunoglobulin (Ig) HC produced: IgA (alpha-HCD), IgG (gamma-HCD), and IgM (mu-HCD).
Thomas E, Witzig +1 more
openaire +2 more sources
The heavy chain diseases (HCDs) are rare B-cell malignancies that are distinguished by the production of a monoclonal immunoglobulin heavy chain (HC) without an associated light chain by the malignant B-cells. There are three types of HCD defined by the class of immunoglobulin (Ig) HC produced: IgA (alpha-HCD), IgG (gamma-HCD), and IgM (mu-HCD).
Thomas E, Witzig +1 more
openaire +2 more sources
Archives of Internal Medicine, 1972
To the Editor. —We read with interest the paper in the September issue1 on αheavy chain disease in which the pathological immunoglobulin disappeared with chemotherapy. The authors state that up to the time of acceptance of their paper all cases of so-called Mediterranean lymphoma and α-chain disease have occurred either in Arabs or oriental Jews in ...
B H, Novis, S, Bank
openaire +3 more sources
To the Editor. —We read with interest the paper in the September issue1 on αheavy chain disease in which the pathological immunoglobulin disappeared with chemotherapy. The authors state that up to the time of acceptance of their paper all cases of so-called Mediterranean lymphoma and α-chain disease have occurred either in Arabs or oriental Jews in ...
B H, Novis, S, Bank
openaire +3 more sources
Clinics in Laboratory Medicine, 1986
A review of alpha-heavy chain disease (AHCD) emphasizing its histopathology and associated lesions is presented. Unusual clinicopathologic presentations and modern concepts regarding histogenesis of AHCD in the light of recent immunohistochemical findings are discussed.
P, Haghighi, P L, Wolf
openaire +2 more sources
A review of alpha-heavy chain disease (AHCD) emphasizing its histopathology and associated lesions is presented. Unusual clinicopathologic presentations and modern concepts regarding histogenesis of AHCD in the light of recent immunohistochemical findings are discussed.
P, Haghighi, P L, Wolf
openaire +2 more sources
European Journal of Immunology, 1978
AbstractUsing cultured mouse myeloma cells, it has been possible to derive cells which are now synthesizing products similar to human heavy chain disease proteins. An initial mutant was isolated which synthesized a heavy chain with an internal deletion and a normal light chain.
openaire +2 more sources
AbstractUsing cultured mouse myeloma cells, it has been possible to derive cells which are now synthesizing products similar to human heavy chain disease proteins. An initial mutant was isolated which synthesized a heavy chain with an internal deletion and a normal light chain.
openaire +2 more sources
1986
Heavy chain diseases (HCD) are immunoproliferative disorders characterized by the production of monoclonal immunoglobulin molecules composed of deleted heavy chains devoid of light chains. The diagnosis is established by immunoelectrophoresis (possibly combined to immunoselection) or immunofixation.
openaire +5 more sources
Heavy chain diseases (HCD) are immunoproliferative disorders characterized by the production of monoclonal immunoglobulin molecules composed of deleted heavy chains devoid of light chains. The diagnosis is established by immunoelectrophoresis (possibly combined to immunoselection) or immunofixation.
openaire +5 more sources