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Heavy chain disease: our experience
Clinical Chemistry and Laboratory Medicine (CCLM), 2017Heavy chain disease (HCD) is a rare lymphoproliferative disorder of plasma cells, described for the first time in 1964 by Franklin [1], characterized by production of incomplete monoclonal immunoglobulin heavy chains without associated light chains [2].
Gulli, Francesca +5 more
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Gastric Alpha Heavy Chain Disease
Oncology, 1987Clinicopathological and immunohistological features of 4 cases of gastric lymphomas with alpha-heavy chain disease (AHCD) are described. Clinically there were no reliable features that could distinguish them from the 'western' types of gastric lymphomas (WGL).
M F, Tungekar, Y T, Omar, K, Behbehani
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Osteolytic gamma heavy chain disease
European Journal of Haematology, 1987We report a case of gamma heavy chain disease (GHCD) with several unique features: extensive osteolytic lesions simulating advanced multiple myeloma (MM), skin involvement, under the age of 40 yr, and the appearance of a series of pathological cells with indented or lobulated nuclei. The most remarkable feature is a previously unreported extensive bone
T, Kanoh, H, Nakasato
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Heavy chain deposition disease: The disease spectrum
American Journal of Kidney Diseases, 1999A 45-year-old white woman was found to have microscopic hematuria during her annual physical examination. After a negative urologic workup, she returned 5 months later with nephrotic syndrome, renal insufficiency, and hypocomplementemia. Renal biopsy showed a nodular sclerosing glomerulopathy that could not be further characterized because of ...
N, Kambham +5 more
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Nihon rinsho. Japanese journal of clinical medicine, 1995
Heavy chain diseases (HCDs) are monoclonal, lymphoproliferative disorders characterized by the production of incomplete heavy chains, devoid of light chains. Since the first report of gamma-HCD in 1964, alpha-HCD and mu-HCD have also been described. The clinical features of gamma-HCD may vary considerably.
S, Nomura, T, Kanoh
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Heavy chain diseases (HCDs) are monoclonal, lymphoproliferative disorders characterized by the production of incomplete heavy chains, devoid of light chains. Since the first report of gamma-HCD in 1964, alpha-HCD and mu-HCD have also been described. The clinical features of gamma-HCD may vary considerably.
S, Nomura, T, Kanoh
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1991
The heavy chain disease is a “true” form of paraproteinemia. The existance of the μ, γ, and α heavy chain disease is well documented. The δ-type heavy chain seems to be a special form of a IgD-myeloma (20, 102). The immunochemical differences within the — μ, γ, α — are accompanied with specific clinical symptoms.
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The heavy chain disease is a “true” form of paraproteinemia. The existance of the μ, γ, and α heavy chain disease is well documented. The δ-type heavy chain seems to be a special form of a IgD-myeloma (20, 102). The immunochemical differences within the — μ, γ, α — are accompanied with specific clinical symptoms.
openaire +1 more source
New roads and challenges for fuel cells in heavy-duty transportation
Nature Energy, 2021David A Cullen +2 more
exaly
The assembly, regulation and function of the mitochondrial respiratory chain
Nature Reviews Molecular Cell Biology, 2021Irene Vercellino, Leonid A Sazanov
exaly
Status and perspectives of crystalline silicon photovoltaics in research and industry
Nature Reviews Materials, 2022Christophe Ballif +2 more
exaly