Results 301 to 310 of about 634,218 (335)
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La Ricerca in Clinica e in Laboratorio, 1976
Human heavy chain diseases offer an opportunity to examine the molecular events taking place in cells which produce naturally occurring structural variants of a well-studied complex protein. Extensive structural analyses have been carried out on many of these proteins and have revealed the existence of certain characteristic features.
Joel N. Buxbaum, Joel N. Buxbaum
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Human heavy chain diseases offer an opportunity to examine the molecular events taking place in cells which produce naturally occurring structural variants of a well-studied complex protein. Extensive structural analyses have been carried out on many of these proteins and have revealed the existence of certain characteristic features.
Joel N. Buxbaum, Joel N. Buxbaum
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Rheumatoid arthritis terminating in heavy-chain disease.
Annals of Internal Medicine, 1969The eighth known case of heavy-chain disease is reported. Immunochemical studies of abnormal Fc fragment gamma-G3 protein and detailed morphologic, chromosomal, and electron microscopic ob...
Z. Zawadzki +3 more
semanticscholar +1 more source
Heavy chain disease: our experience
Clinical Chemistry and Laboratory Medicine (CCLM), 2017Heavy chain disease (HCD) is a rare lymphoproliferative disorder of plasma cells, described for the first time in 1964 by Franklin [1], characterized by production of incomplete monoclonal immunoglobulin heavy chains without associated light chains [2].
Gulli, Francesca +5 more
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1986
Heavy chain diseases (HCD) are immunoproliferative disorders characterized by the production of monoclonal immunoglobulin molecules composed of deleted heavy chains devoid of light chains. The diagnosis is established by immunoelectrophoresis (possibly combined to immunoselection) or immunofixation.
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Heavy chain diseases (HCD) are immunoproliferative disorders characterized by the production of monoclonal immunoglobulin molecules composed of deleted heavy chains devoid of light chains. The diagnosis is established by immunoelectrophoresis (possibly combined to immunoselection) or immunofixation.
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The evolution of alpha heavy chain disease
The American Journal of Medicine, 1976Two patients with alpha heavy chain disease are described. In the first patient, treatment with cyclophosphamide, prednisone and doxycycline was associated with a 28 month-long remission and the disappearance of the paraprotein and lymphoplasmocytic infiltration of the intestine.
Martínez-Vázquez Jm +6 more
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Cutaneous Lesions in ? Heavy-Chain Disease [PDF]
Archives of Dermatology, 1988 • Erythematous, infiltrated plaques and extensive, heavy pleomorphic lymphoid cell infiltrates of the dermis were observed in a patient with γ heavy-chain disease. ( Arch Dermatol 1988;124:1538-1540)
Yukie Niwa +2 more
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Gastric Alpha Heavy Chain Disease
Oncology, 1987Clinicopathological and immunohistological features of 4 cases of gastric lymphomas with alpha-heavy chain disease (AHCD) are described. Clinically there were no reliable features that could distinguish them from the 'western' types of gastric lymphomas (WGL).
Y.T. Omar, M.F. Tungekar, K. Behbehani
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Diagnosis of Gamma Heavy-Chain Disease
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1981The diagnosis of gamma heavy-chain disease can be made only by immunochemical analysis of serum and urine. The case reported here demonstrates the importance of diligent observation of routine electrophoretic patterns, followed by immunoelectrophoresis where indicated for the identification of abnormal bands.
K R Hine +3 more
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Alpha heavy chain disease. A variant of Mediterranean lymphoma.
Archives of Internal Medicine, 1971The Mediterranean type of abdominal lymphoma has recently been described as a separate disease entity by Ramot et al, 1 Eidelman et al, 2 and Seijffers et al.
A. Zlotnick, M. Levy
semanticscholar +1 more source
Gamma heavy chain disease. Reports of three patients.
Acta Medica Scandinavica, 2009Three cases of γ-heavy chain disease (γ-HCD) are reported. Two of the patients had a clinical picture of malignant lymphoma, similar to most of the cases earlier described.
J. Westin +6 more
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