Results 51 to 60 of about 646,837 (299)
Probing QED Vacuum with Heavy Ions
, 2016 We recall how nearly half a century ago the proposal was made to explore the structure of the quantum vacuum using slow heavy-ion collisions. Pursuing this topic we review the foundational concept of spontaneous vacuum decay accompanied by observable ...
Greiner, Walter +4 more
core +1 more source
One and Two-photon Physics with Relativistic Heavy Ions [PDF]
, 2001 The physics of peripheral collisions with relativistic heavy ions (PCRHI) is reviewed. One- and two-photon processes are discussed.Comment: 14 pages, Invited talk at the 17th Winter Workshop on Nuclear Dynamics, Park City, Utah, March 10-17 ...
Bertulani, C. A.
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Nanolesions induced by heavy ions in human tissues: experimental and theoretical studies [PDF]
, 2012 The biological effects of energetic heavy ions are attracting increasing interest for their applications in cancer therapy and protection against space radiation.
Cathrin Wälzlein +12 more
core +2 more sources
The State of Solar Wind Heavy Ions in Interplanetary Coronal Mass Ejection–Driven Geomagnetic Storms
The Astrophysical JournalDuring geomagnetic storms, which are the primary periods for heavy ions from the solar wind to enter Earth’s magnetospheric space, the charge state of solar wind heavy ions during these storms has significant implications for studying the distribution ...
Cong Wang, Fei He, Xiaoxin Zhang
doaj +1 more source
Equilibrium in Heavy Ion Collisions [PDF]
Acta Physica Hungarica A) Heavy Ion Physics, 2004 Proceedings 19th Winter Workshop on Nuclear Dynamics, Breckenridge, Co ...
Koch, Volker, Majumder, Abhijit
openaire +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source