Results 11 to 20 of about 295,434 (259)
Anthropogenic heavy metals in organic forest soils [PDF]
The continuous heavy metal accumulation in organic topsoils in forests will pose problems for soil microbial health for many years to come. The primary objective of this thesis was to investigate heavy metal pollution in forest soils and its effects on ...
Åkerblom, Staffan
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Bacteria in heavy metal contaminated soil: diversity, tolerance and use in remediation [PDF]
The objectives of this project were to determine the bacterial diversity in a heavily contaminated metal region of Portugal. Both traditional and molecular based methods were used to identify tolerant strains and species. The most tolerant species were
Pires, Carlos
core
Riverine transfer of heavy metals from Patagonia to the southwestern Atlantic Ocean [PDF]
The occurrence and geochemical behaviour of Fe, Mn, Pb, Cu, Ni, Cr, Zn and Co are studied in riverine detrital materials transported by Patagonian rivers.
Probst, Jean-Luc +8 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Effect of heavy metal stress in plant metabolism of solanaceous plant species with emphasis on nitrogen assimilation [PDF]
Several plant species are able to accumulate and withstand large quantities of heavy metals in their tissues without dramatic alterations in their growth usually observed in plants. Such metal accumulating plants are tested and used for remediation of
Christofaki, Maria Ioannou
core
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source

