Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
Environmental impact of Italian pig herds as affected by farm management factors
This study aimed at evaluating the environmental impact (EI) of herds representative of the Italian heavy pig production system to investigate the EI variation associated with farm management (FM), diet formulation (DF) and animal response (AR) variables.
Marco Berton +4 more
doaj +1 more source
SWINE WASTE PHYTOREMEDIATION USING DUCKWEED (Landoltia punctata, Les & Crawford) IN A FULL SCALE PLANT [PDF]
Banner Apresentado em Congresso: 11th International Conference, Heraklion, Crete, Greece PhytotechnologiesThe large amount of nitrogen and phosphorous compounds found in pig manure has caused ecological imbalances, with eutrophication of major river ...
Belli Filho, Paulo +2 more
core
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs
Here, we have established an antigen-specific single B cell sorting and monoclonal antibody (mAb) cloning platform for analyzing immunization- or viral infection-elicited antibody response at the clonal level in guinea pigs.
Lin Lei +9 more
doaj +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
Lack of cardiac differentiation in c-kit-enriched porcine bone marrow and spleen hematopoietic cell cultures using 5-azacytidine [PDF]
The adult spleen is a source of early hematopoietic stem cells (HSC). We therefore studied whether culturing spleen or bone marrow (BM) HSC in medium containing 5-azacytidine could induce a cardiac phenotype.
Cooper, D.K.C. (David) +6 more
core +2 more sources
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni +4 more
wiley +1 more source
Efficiency of an Integrated Purification System for Pig Slurry Treatment under Mediterranean Climate
The intensification of pig production is considered a risky activity for the environment when the generated pig slurry is not adequately treated. In addition, intensive agriculture practices where pig slurry is applied to the cropland could cause nitrate
Martire Angélica Terrero +4 more
doaj +1 more source

