Results 51 to 60 of about 26,472 (303)

Simulating mixture of sub-Gaussian spatial data [PDF]

open access: yesAUT Journal of Mathematics and Computing
Spatial datasets may contain extreme values and exhibit heavy tails. So, the Gaussianity assumption for the corresponding random field is not reasonable. A sub-Gaussian α-stable (SGαS) random field may be more suitable as a model for heavy-tailed spatial
Seyedeh Somayeh Mousavi   +1 more
doaj   +1 more source

seananderson/heavy-tails-response: heavy-tails-response v1.0

open access: yes, 2017
<p>This repository contains data and code for the letter: Anderson SC, Branch TA, Cooper AB, Dulvy NK. 2017. Reply to Youngflesh and Lynch: Migration and population growth rate in animal black-swan events.
Sean Anderson
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Modeling Air Pollution Using Partially Varying Coefficient Models with Heavy Tails

open access: yesMathematics, 2022
The increase in air pollution levels in recent decades around the world has caused a negative impact on human health. A recent investigation by the World Health Organization indicates that nine out of ten people on the planet breathe air containing high ...
Nicole Jeldes   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Regret Minimization in Heavy-Tailed Bandits

open access: yesCoRR, 2021
35 pages, 2 ...
S. Agrawal (Shubhada)   +2 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Asymptotic behaviour of non-isotropic random walks with heavy tails

open access: yesModern Stochastics: Theory and Applications, 2017
A random flight on a plane with non-isotropic displacements at the moments of direction changes is considered. In the case of exponentially distributed flight lengths a Gaussian limit theorem is proved for the position of a particle in the scheme of ...
Mark Kelbert, Enzo Orsingher
doaj   +1 more source

Extremal behavior of stochastic volatility models [PDF]

open access: yes, 2005
Empirical volatility changes in time and exhibits tails, which are heavier than normal. Moreover, empirical volatility has - sometimes quite substantial - upwards jumps and clusters on high levels.
Lindner, Alexander M.   +7 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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