Results 51 to 60 of about 888,711 (295)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Long Range Dependence, Heavy Tails and Rare Events [PDF]
, 2002 Long Range Dependence, Heavy Tails and Rare ...
Samorodnitsky, G.
core +5 more sources
Heavy Tails in Program Structure
IEEE Computer Architecture Letters, 2017 Designing and optimizing computer systems require deep understanding of the underlying system behavior. Historically many important observations that led to the development of essential hardware and software optimizations were driven by empirical observations about program behavior. In this paper, we report an interesting property of program structures
Hiroshi Sasaki 0001 +3 more
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Modeling Air Pollution Using Partially Varying Coefficient Models with Heavy Tails
Mathematics, 2022 The increase in air pollution levels in recent decades around the world has caused a negative impact on human health. A recent investigation by the World Health Organization indicates that nine out of ten people on the planet breathe air containing high ...
Nicole Jeldes +3 more
doaj +1 more source
Regret Minimization in Heavy-Tailed Bandits
CoRR, 2021 35 pages, 2 ...
S. Agrawal (Shubhada) +2 more
openaire +5 more sources
Extremal behavior of stochastic volatility models [PDF]
, 2005 Empirical volatility changes in time and exhibits tails, which are heavier than normal. Moreover, empirical volatility has - sometimes quite substantial - upwards jumps and clusters on high levels.
Lindner, Alexander M. +7 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Inference for double Pareto lognormal queues with applications [PDF]
, 2008 In this article we describe a method for carrying out Bayesian inference for the double Pareto lognormal (dPlN) distribution which has recently been proposed as a model for heavy-tailed phenomena. We apply our approach to inference for the dPlN/M/1 and
Lillo Rodríguez, Rosa Elvira +3 more
core +1 more source
Asymptotic behaviour of non-isotropic random walks with heavy tails
Modern Stochastics: Theory and Applications, 2017 A random flight on a plane with non-isotropic displacements at the moments of direction changes is considered. In the case of exponentially distributed flight lengths a Gaussian limit theorem is proved for the position of a particle in the scheme of ...
Mark Kelbert, Enzo Orsingher
doaj +1 more source