Results 61 to 70 of about 888,711 (295)

Tail behavior of negatively associated heavy-tailed sums [PDF]

Journal of Applied Probability, 2006
Consider a sequence {Xk, k ≥ 1} of random variables on (−∞, ∞). Results on the asymptotic tail probabilities of the quantities , and S(n) = max0 ≤ k ≤ nSk, with X0 = 0 and n ≥ 1, are well known in the case where the random variables are independent with a heavy-tailed (subexponential) distribution.
Geluk, J, Ng, KW
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Optimal Trade Execution under Jump Diffusion Process: A Mean-VaR Approach

Discrete Dynamics in Nature and Society, 2018
In the classical optimal execution problem, the basic assumption of underlying asset price is Arithmetic Brownian Motion (ABM) or Geometric Brownian Motion (GBM).
Tianmin Zhou, Can Jia, Handong Li
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Constructing a geography of heavy-tailed flood distributions: insights from common streamflow dynamics [PDF]

Hydrology and Earth System Sciences
Heavy-tailed flood distributions depict the higher occurrence probability of extreme floods. Understanding the spatial distribution of heavy-tail floods is essential for effective risk assessment.
H.-J. Wang, R. Merz, R. Merz, S. Basso
doaj   +1 more source

Environmental concentrations as ratios of random variables

Environmental Research Letters, 2022
Human-induced environmental change increasingly threatens the stability of socio-ecological systems. Careful statistical characterization of environmental concentrations is critical to quantify and predict the consequences of such changes on human and ...
Saverio Perri, Amilcare Porporato
doaj   +1 more source

Derivation of the Fractional Fokker–Planck Equation for Stable Lévy with Financial Applications

Mathematics, 2023
This paper aims to propose a generalized fractional Fokker–Planck equation based on a stable Lévy stochastic process. To develop the general fractional equation, we will use the Lévy process rather than the Brownian motion.
Reem Abdullah Aljethi, Adem Kılıçman
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Estimation and tests for power-transformed and threshold GARCH models [PDF]

, 2008
Consider a class of power transformed and threshold GARCH(p,q) (PTTGRACH(p,q)) model, which is a natural generalization of power-transformed and threshold GARCH(1,1) model in Hwang and Basawa (2004) and includes the standard GARCH model and many other ...
Tong, H., Wang, Hui, Wang, H., Tong, Howell, Pan, Jiazhu, Pan, J.   +5 more
core   +3 more sources

The Spectrum of Heavy Tailed Random Matrices [PDF]

Communications in Mathematical Physics, 2007
Let $X_N$ be an $N\ts N$ random symmetric matrix with independent equidistributed entries. If the law $P$ of the entries has a finite second moment, it was shown by Wigner \cite{wigner} that the empirical distribution of the eigenvalues of $X_N$, once renormalized by $\sqrt{N}$, converges almost surely and in expectation to the so-called semicircular ...
Ben Arous, Gerard, Guionnet, Alice
openaire   +4 more sources