Results 61 to 70 of about 31,275 (267)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Detecting Covid-19 Fake News on Twitter/X in French: Deceptive Writing Strategies

open access: yesMedia and Communication
Many who believed Covid-19 fake news eschewed vaccines, masks, and social distancing; got unnecessarily infected; and died. To detect such fake news, we follow deceptive writing theory and link French hedges and modals to validity.
Ming Ming Chiu   +3 more
doaj   +1 more source

A Corpus-Based Study on Cross-Cultural Divergence in the Use of Hedges in Academic Research Articles Written by Vietnamese and Native English-Speaking Authors

open access: yesSocial Sciences, 2018
As an interpersonal meta-discourse device, hedges have a significant role in academic writing, especially in research articles (RAs) of various fields. The use of hedges in academic writing helps writers represent their ideology, opinion, and evaluation ...
Thu Nguyen Thi Thuy
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Development and validation of a search filter to identify equity-focused studies: reducing the number needed to screen

open access: yesBMC Medical Research Methodology, 2018
Background Health inequalities, worse health associated with social and economic disadvantage, are reported by a minority of research articles. Locating these studies when conducting an equity-focused systematic review is challenging due to a deficit in ...
Stephanie L Prady   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Genderlect as discourse in Yoruba movies

open access: yesCrossroads, 2016
This paper offers an analysis of gender discourse of Yoruba male and female movie characters. The Yoruba speech community is one of the three major ethnic groups in Nigeria.
Joseph Babasola Osoba   +1 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

A Metadiscourse Study of Boosters and Hedges in Research Article Abstracts

open access: yesCorporum, 2018
Metadiscourse serves as a tool for building relationship between the author and the reader, and among the text and the audience by enhancing the communicative tendency of the discourse.
Sana Zafar
doaj  

Cross-Cultural Variation in the Use of Hedges and Boosters in Academic Discourse

open access: yesPrague Journal of English Studies, 2016
Hedges and boosters are important metadiscoursal devices contributing to the construal of persuasion in academic discourse as they enable academic writers to distinguish facts from opinions, evaluate the views of others and convey a different degree of ...
Dontcheva-Navratilova Olga
doaj   +1 more source

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