Results 1 to 10 of about 76,072 (118)

Heel hidradenocarcinoma regarded as a corn for 25 years with subsequent multiorgan metastasis: a case report and literature review [PDF]

Frontiers in Oncology
BackgroundHidradenocarcinoma is a rare malignant cutaneous adnexal tumor with nonspecific clinical features. Heel involvement is uncommon and may be mistaken for a benign hyperkeratotic or pressure-related lesion.Case presentationA 44-year-old woman was ...
Lianbo Yang, Ziang Zheng, Haoran Chen, Xinyao Cui, Jiabin Lin, Yifan Wang, Haidong Liang, Jing Yi   +7 more
doaj   +2 more sources

Comparing Free and Pedicled Flaps for Leg, Ankle and Heel Reconstruction: An Analysis of Outcomes, Complications and Flap Selection Considerations [PDF]

Medical Sciences
Background/Objectives: Reconstruction of defects in the ankle, foot and heel is complex because of the limited availability of local tissue and multiple comorbidities like diabetes mellitus and peripheral vascular disease.
Claudiu Ioan Filip, Radu Alexandru Ilieș, David Andraș, Alexandra Caziuc, George Călin Dindelegan   +4 more
doaj   +2 more sources

A problem-based approach in musculoskeletal ultrasonography: heel pain in adults [PDF]

Ultrasonography, 2022
Musculoskeletal ultrasonography (US) has unique advantages, such as excellent spatial resolution for superficial structures, the capability for dynamic imaging, and the ability for direct correlation and provocation of symptoms.
Yong Hee Kim, Jee Won Chai, Dong Hyun Kim, Hyo Jin Kim, Jiwoon Seo   +4 more
doaj   +1 more source

The Multicomponent Medicinal Product Hepar Compositum Reduces Hepatic Inflammation and Fibrosis in a Streptozotocin- and High-Fat Diet-Induced Model of Metabolic Dysfunction-Associated Steatotic Liver Disease/Metabolic Dysfunction-Associated Steatohepatitis

Biomedicines, 2023
Metabolic dysfunction-associated steatotic liver disease (MASLD)—formerly known as non-alcoholic fatty liver disease (NAFLD)—is the most common chronic liver disease worldwide.
Yvonne Burmeister, Kathrin Weyer, Achim Dörre, Bernd Seilheimer   +3 more
doaj   +1 more source

Medial plantar flap for reconstruction of heel defects after resection of acral lentiginous melanoma: A series of seven cases [PDF]

Revista Brasileira de Cirurgia Plástica, 2023
Introduction: Resurfacing the sole is still one of the great challenges of reconstructive plastic surgery. The tissues on the sole of the foot have unique characteristics essential for maintaining the limbs functionality.
Giulia Godoy Takahashi, Renan Diego Américo Ribeiro, Vitor Penteado Figueiredo Pagotto, Caio Augusto Lima de Araújo, Fábio de Freitas Busnardo, Rolf Gemperli   +5 more
doaj   +1 more source

Network analyses reveal new insights into the effect of multicomponent Tr14 compared to single-component diclofenac in an acute inflammation model

Journal of Inflammation, 2023
Background Modifying the acute inflammatory response has wide clinical benefits. Current options include non-steroidal anti-inflammatory drugs (NSAIDs) and therapies that may resolve inflammation.
Matti Hoch, Suchi Smita, Konstantin Cesnulevicius, Myron Schultz, David Lescheid, Olaf Wolkenhauer, Shailendra Gupta   +6 more
doaj   +1 more source

The Natural Combination Medicine Traumeel (Tr14) Improves Resolution of Inflammation by Promoting the Biosynthesis of Specialized Pro-Resolving Mediators

Pharmaceuticals, 2021
The resolution of inflammation is an integral part of the acute inflammatory response and eventually leads to the return to homeostasis. It is supported by specialized pro-resolving mediators (SPMs) that act as immunoresolvents via specific G-protein ...
Paul M. Jordan, Emeline van Goethem, Andrea M. Müller, Kathrin Hemmer, Virginie Gavioli, Vincent Baillif, Yvonne Burmeister, Natascha Krömmelbein, Marc Dubourdeau, Bernd Seilheimer, Oliver Werz   +10 more
doaj   +1 more source

Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps

npj Systems Biology and Applications, 2022
Complex diseases are inherently multifaceted, and the associated data are often heterogeneous, making linking interactions across genes, metabolites, RNA, proteins, cellular functions, and clinically relevant phenotypes a high-priority challenge. Disease
Matti Hoch, Suchi Smita, Konstantin Cesnulevicius, David Lescheid, Myron Schultz, Olaf Wolkenhauer, Shailendra Gupta   +6 more
doaj   +1 more source

Vertigoheel promotes rodent cognitive performance in multiple memory tests

Frontiers in Neuroscience, 2023
IntroductionCognitive impairment associated with old age or various brain disorders may be very disabling for affected individuals, placing their carers and public health services under considerable stress.
Kerstin Ott, Taneli Heikkinen, Kimmo K. Lehtimäki, Kaisa Paldanius, Jukka Puoliväli, Raimo Pussinen, Emile Andriambeloson, Bertrand Huyard, Stéphanie Wagner, Cathrin Schnack, Anke Wahler, Bjoern von Einem, Christine A. F. von Arnim, Christine A. F. von Arnim, Yvonne Burmeister, Kathrin Weyer, Bernd Seilheimer   +16 more
doaj   +1 more source

RNAseq analysis of treatment-dependent signaling changes during inflammation in a mouse cutaneous wound healing model

BMC Genomics, 2021
Background Despite proven therapeutic effects in inflammatory conditions, the specific mechanisms of phytochemical therapies are not well understood. The transcriptome effects of Traumeel (Tr14), a multicomponent natural product, and diclofenac, a non ...
Georges St. Laurent, Ian Toma, Bernd Seilheimer, Konstantin Cesnulevicius, Myron Schultz, Michael Tackett, Jianhua Zhou, Maxim Ri, Dmitry Shtokalo, Denis Antonets, Tisha Jepson, Timothy A. McCaffrey   +11 more
doaj   +1 more source