Results 171 to 180 of about 613,957 (389)

HeLa [PDF]

, 2020
openaire   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

DNA methylases separated through the HeLa cell cycle methodology show allosteric properties (19887) [PDF]

, 1988
C. Delfini, A.L. Crema, E. Alfani, E.Lo Presti, T. Eremenko, P. Volpe   +5 more
openalex   +1 more source

Preparation of Artemisia turcomanic encapsulated niosomal nanocarrier and evaluation of anti-cancer activities and apoptosis gene expression analysis in uterine cancer cell lines (Hela) [PDF]

, 2022
farnaz eslamian, Zahra Keshtmand, Ardeshir Hesampour   +2 more
openalex   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative

Open Chemistry, 2010
Alexandru Maria-Gabriela, Velickovic Tanja, Jitaru Ioana, Grguric-Sipka Sanja, Draghici Constantin   +4 more
doaj   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Development of the Curcumin Analog CA7 Liposome and Its Evaluation for Efficacy Against Cervical Cancer in vitro and in vivo

International Journal of Nanomedicine
Linjin Xiong,1– 4,* Yumeng Wei,1,3,* Hui Si,4,* Zheng Li,1– 3 Jie Wen,1– 3 Furong Liu,5 Xiaodong Wang,6 Hongru Yang,7 Ligang Chen,8 Chao Pi,1,3 Yunwei Han,7 Ling Zhao2– 4 1Key Laboratory of Medical Electrophysiology, Ministry of Education ...
Xiong L, Wei Y, Si H, Li Z, Wen J, Liu F, Wang X, Yang H, Chen L, Pi C, Han Y, Zhao L   +11 more
doaj  

Exploring In‐Silico, In‐Vitro Antioxidant, and Cytotoxic Potential of Valerian wallichii by On Cervical Epithelial Carcinoma (HeLa) Cell Lines [PDF]

Sachin Gudasi, Shankar Gharge, Rahul Koli, Pooja Kagawad   +3 more
openalex   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source