Results 201 to 210 of about 592,638 (373)
Advanced Science, EarlyView.This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing +18 more
wiley +1 more source
VIROLOGICAL AND ELECTRONMICROSCOPIC STUDIES ON THE GROWTH OF VARIOLA VIRUS IN CULTURED HELA CELLS
, 1959 一宮 昌代
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Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
Advanced Science, EarlyView.The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia +12 more
wiley +1 more source
ROLE OF CHICK EMBRYO EXTRACT FOR GROWTH MODE IN VITRO OF HUMAN CARCINOMA HELA STRAIN CELLS1)
, 1957 Kouichi Takano
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Changes in lipid pattern of HeLa cells exposed to immunoglobulin G and complement [PDF]
, 1969 Flemming Güttler, Jørgen Clausen
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Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
Advanced Science, EarlyView.The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su +12 more
wiley +1 more source
Differential Inhibition of Attachment and Eclipse Activities of HeLa Cells for Enteroviruses [PDF]
, 1969 Ian Zajac, Richard L. Crowell
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Advanced Science, EarlyView.A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen +9 more
wiley +1 more source
THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATION
, 1967 Elliott Robbins, Thaddeus W. Borun
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