Results 231 to 240 of about 592,638 (373)

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

Advanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou, Binghua Zhang, Lang Liu, Jie Yang, Yuting Wang, Cheng Lv, He Zhang, Yuchi Wei, Zhanliang Jiang, Zeyu Peng, Daqing Zhao, Xiangyang Leng, Xiangyan Li, Hang Su, Haisi Dong   +14 more
wiley   +1 more source

DNA hypomethylation modification promotes BST2 expression in cervical cancer by facilitating STAT1 binding to the promoter of BST2. [PDF]

Infect Agent Cancer
Wubuli R, Ainiwaer Z, Niyazi M, Han L.
europepmc   +1 more source

Programming of Poliovirus Inhibition of Deoxyribonucleic Acid Synthesis in HeLa Cells [PDF]

, 1966
W. W. Ackermann, Daniel Wahl
openalex   +1 more source

A Dual‐Targeting T6SS DNase Drives Bacterial Antagonism and Eukaryotic Apoptosis via the cGAS‐STING‐TNF Axis

Advanced Science, EarlyView.
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song, Lei Xu, Pengfei Zhang, Shuying Li, Yichen Qu, Yixin Zhao, Zhenkun Shi, Ruiqi Ma, Yongdong Li, Yi Chen, Yao Wang, Zhengfan Jiang, Gehong Wei, Xihui Shen   +13 more
wiley   +1 more source

Neocarzilin A induces apoptosis and mitochondrial disturbance by targeting reticulon 4-mediated endoplasmic reticulum stress. [PDF]

Cell Death Discov
Jauch AT, Sailer J, Braun J, Czeslik E, Geyer J, Eberhagen C, Vollmar AM, Zischka H, Sieber SA, Zahler S.   +9 more
europepmc   +1 more source

CELL CYCLE EVENTS IN THE HYDROCORTISONE REGULATION OF ALKALINE PHOSPHATASE IN HELA S3 CELLS

, 1969
Martin J. Griffin, Raphael Ber
openalex   +1 more source

�ber die antikomplement�re Aktivit�t von Antigenen aus normalen und mit Vaccinevirus infizierten HeLa-Zellkulturen [PDF]

, 1961
R. Wigand
openalex   +1 more source

Engineering Liquid Hierarchical Materials with DNA‐Programmed Spherical Nucleic Acids

Advanced Science, EarlyView.
Programmable spherical nucleic acids assembly strategies for constructing hierarchical structures through engineered DNA bond to form novel liquid‐like metal droplets. Abstract Inspired by nature, the orchestration of self‐assembling building blocks into hierarchical superstructures offers a transformative approach to functional materials design. While 
Zeyu Chen, Xu Chen, Dan Lu, Huating Kong, Jingyi Ye, Chunhai Fan, Honglu Zhang, Huan Zhang   +7 more
wiley   +1 more source

Inhibiting CMTM4 reverses the immunosuppressive function of myeloid-derived suppressor cells and augments immunotherapy response in cervical cancer. [PDF]

J Immunother Cancer
Ding J, Hu H, Zhu Y, Xu X, Yin B, Yang M, Zhou H, Huang T, Li M, Kou Y, Rahim Z, Huang B, Li A, Wang W, Han L.   +14 more
europepmc   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

Advanced Science, EarlyView.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu, Suhui He, Wen Shi, Jinxia Xu, Shiyang Liu, Zexu Yu, Danyue Li, Qiao Jin, Yumeng Wang, Zian Zhang, Qian Lv, Yuanxiang Ge, Yunjie Li, Xinyue Li, Nan Chen, Xinyu Fu, Yang Yang, Fushan Shi   +17 more
wiley   +1 more source