Results 241 to 250 of about 592,638 (373)

GSK3A promotes human adenovirus replication and phosphorylates viral L4-22K protein. [PDF]

open access: yesLife Sci Alliance
Lin Y   +6 more
europepmc   +1 more source

Mitigating Cell Cycle Effects in Multi‐Omics Data: Solutions and Analytical Frameworks

open access: yesAdvanced Science, EarlyView.
The study highlights the cell‐cycle effects on multi‐omics analysis attributed to varying cell cycle compositions across cell types. To minimize the influence, we propose RTD correction in CNV calling with a high S‐phase ratio, and phase comparison in chromatin accessibility, DNA methylation, and transcriptomics.
Rui Nie   +7 more
wiley   +1 more source

Kiel Data Management Infrastructure for Marine Sciences [PDF]

open access: yes, 2013
Czerniak, Andreas   +4 more
core  

Chemigenetic Encoding of Fluorescent Dyes Enables High‐Fidelity and Wash‐Free Imaging of Proteins in Live Cells

open access: yesAdvanced Science, EarlyView.
This study develops a chemigenetic strategy that combines synthetic dyes with genetically encoded fluorescence for high‐fidelity, no‐wash protein imaging. By utilizing FRET between fluorescent proteins and Halo‐tag dyes, this system ensures that only target‐bound dyes fluoresce, effectively suppressing background signals and enhancing the signal‐to ...
Xuelian Zhou   +8 more
wiley   +1 more source

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