Results 261 to 270 of about 613,957 (389)
Deep Learning‐Assisted Coherent Raman Scattering Microscopy
Advanced Intelligent Discovery, EarlyView.The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu +4 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.A 3D holotomography system coupled with a deep learning model distinguishes how cells die—apoptosis, necroptosis or necrosis—without any fluorescent labels. Training on refractive index maps of HeLa cells yields 97% accuracy and flags necroptosis hours before chemical dyes.
Minwook Kim +8 more
wiley +1 more source
Controlled intra- and extracellular localization of bioorthogonal polymeric nanozymes. [PDF]
Chem SciHirschbiegel CM +8 more
europepmc +1 more source
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Proceedings of the National Academy of Sciences of the United States of America, 1992 M. Gossen, H. Bujard
semanticscholar +1 more source
Rod‐Like PLGA Microrobots with Enhanced Motion and Biodegradation for Magnetic‐Guided Drug Delivery
Advanced Intelligent Systems, EarlyView.This study presents drug‐loaded Poly (lactic‐co‐glycolic acid) (PLGA) microrobots fabricated from an oil‐in‐water (O/W) emulsion of PLGA, Fe3O4 nanoparticles, and Adriamycin (DOX). They are formed by film‐forming and stretching microrobots, and exhibit motion analyzed via video‐snapshots, speed graphs, and shape changes, advancing targeted for drug ...
Junkai Zhang +6 more
wiley +1 more source
Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling
Angewandte Chemie, EarlyView.We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková +4 more
wiley +2 more sources
Long-Patch Base Excision Repair of 5'-DNA-Peptide Cross-Links Derived from Abasic DNA Lesions. [PDF]
BiochemistryBryan C, Cepeda J, Wei X, Yang K.
europepmc +1 more source