Results 321 to 330 of about 592,638 (373)

Unsaturated Phosphine Oxides for Modular Antibody Rebridging and Single Reagent Peptide‐Cyclisation‐Bioconjugation

open access: yesAngewandte Chemie International Edition, Accepted Article.
Achieving modular, selective and homogeneous protein modifications is of utmost importance for the design of next generation biopharmaceuticals; especially in the context of antibody‐drug conjugates (ADCs). Here, we introduce unsaturated phosphine oxides as versatile triple‐reactive reagents, allowing orthogonal chemoselective bioconjugation schemes ...
Christian E. Stieger   +5 more
wiley   +1 more source

Quantitative Analysis of Fluorescent Sensor Arrays

open access: yesAnalysis &Sensing, EarlyView.
Fluorescent sensor arrays have great potential for the quantification of analytes in complex systems. Herein, statistical multivariate techniques and deep learning models to provide quantitative information from such arrays are reviewed. Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to ...
Karandeep Grover   +3 more
wiley   +1 more source

New Insights into the Anticancer Effects and Toxicogenomic Safety of Two β-Lapachone Derivatives. [PDF]

open access: yesPharmaceuticals (Basel)
De Lima JR   +13 more
europepmc   +1 more source

TRIM22 functions as a scaffold protein for autophagy initiation. [PDF]

open access: yesAnim Cells Syst (Seoul)
Park H   +7 more
europepmc   +1 more source

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