Results 41 to 50 of about 613,957 (389)
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line
Nature, 2013 The HeLa cell line was established in 1951 from cervical cancer cells taken from a patient, Henrietta Lacks. This was the first successful attempt to immortalize human-derived cells in vitro.
Andrew C. Adey +8 more
semanticscholar +1 more source
Anticancer Activity Test Of 70% Alcohol Extract of Sembung Leaves (Blumea Balsamifera) Against Cervical Cancer Cells In-Vitro [PDF]
BIO Web of ConferencesCervical cancer is one of the most common cancers among Indonesian women, second only to breast cancer. Several anticancer medications cause minor to severe adverse effects such as fever, nausea, vomiting, hair loss, and other diseases.
Sari Ni Luh Putu Dian Putri Permata +6 more
doaj +1 more source
Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION. [PDF]
, 2016 The relevance of mitochondrial phosphate carrier (PiC), encoded by SLC25A3, in bioenergetics is well accepted. However, little is known about the mechanisms mediating the cellular impairments induced by pathological SLC25A3 variants.
Acoba, Michelle G. +9 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Cytotoxic activityof cyanobacteria from Geno hot spring on HeLa human cell line [PDF]
بومشناسی آبزیان, 2016 The present study aimed to determine the cellular toxicity and anticancer characteristics of six species of Cyan bacteria living in Geno hot spring on cervical cancer cell lines.
Hadiseh Ebrahimi +3 more
doaj
Pharmaceutical Biology, 2017 Context: Chrozophora tinctoria (L.) A. Juss. (Euphorbiaceae) is known as ‘dyer’s-croton’ and used to obtain dye substances. Recently, natural antioxidants and colorants have been of interest because of their safety and therapeutic effects.
Feyza Oke-Altuntas +4 more
doaj +1 more source
Jurnal Kimia Sains dan Aplikasi, 2010 L-asparaginase adalah enzim hidrolase yang mengkatalisis hidrolisis asparagin menjadi asam aspartat dan amonia. L-asparaginase diketahui membantu pengobatan kanker dengan menghambat sintetis protein sel kanker tanpa merusak sel normal.
Arthuro Romualdo +2 more
doaj +1 more source
Molecules, 2020 Betulinic acid (BA) is a star member of the pentacyclic triterpenoid family, which exhibits great prospects for antitumor drug development. In an attempt to develop novel antitumor candidates, 21 BA-nitrogen heterocyclic derivatives were synthetized, in ...
Yuqin Yang +14 more
doaj +1 more source
Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway [PDF]
, 1993 Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional design
Curiel, David T. +5 more
core +2 more sources
PLoS ONE, 2014 The new concept of Immunogenic Cell Death (ICD), associated with Damage Associated Molecular Patterns (DAMPs) exposure and/or release, is recently becoming very appealing in cancer treatment.
E. Panzarini +3 more
semanticscholar +1 more source