Results 61 to 70 of about 613,957 (389)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Implementation of Solar Energy Tracking System

open access: yesJournal of Engineering and Sustainable Development, 2014
Solar energy is one of the best option for electrical energy generation as it is available everywhere and it is renewable. To generate electrical energy from solar energy the solar photovoltaic panels are used.
Manal H. Jassim, Ali Reyadh Waheed
doaj  

Examination of Telomerase Expression with Immuno-Hystochemistry Techniques on Some of Cancer Cells

open access: yesMakara Journal of Health Research, 2016
Background: Cancer is a disease that gets serious attention in the medical world. This is due to the ever increasing number of patients and there has been no effective way to treat.
Endang Purwaningsih   +2 more
doaj   +1 more source

Data Management: The Data Life Cycle [PDF]

open access: yes, 2012
The scientific site of Kiel provides support for projects with data management requirements due to project size or interdisciplinarity. This infrastructure is the Kiel Data Management Infrastructure (KDMI) and was initially created by SFB574, SFB754 ...
Czerniak, Andreas   +4 more
core  

Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus [PDF]

open access: yes, 1996
The methyl-CpG binding domain (MBD) proteins are key molecules in the interpretation of DNA methylation signals leading to gene silencing. We investigated their binding specificity at the constitutively methylated region of a CpG island containing the ...
Auriol, Emilie   +3 more
core   +2 more sources

Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs

open access: yesPLoS ONE, 2014
Sphingolipids are essential components in eukaryotes and have various cellular functions. Recent developments in genome-editing technologies have facilitated gene disruption in various organisms and cell lines.
T. Yamaji, K. Hanada
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Antioxidant and Antitumor Activities of Novel Quercetin-Loaded Electrospun Cellulose Acetate/Polyethylene Glycol Fibrous Materials

open access: yesAntioxidants, 2020
The aim of present study was to obtain novel fibrous materials based on cellulose derivative and polyethylene glycol loaded with natural biologically active compound quercetin by electrospinning.
Nikoleta Stoyanova   +5 more
doaj   +1 more source

International Management, Should We Abandon the Myth of Cultural Hybridity? A Re-examination of the Contribution of Postcolonial and Decolonial Approaches

open access: yesM@n@gement, 2021
The postcolonial and decolonial approaches open the way for a rich analysis of the material and cultural conditions in which international management operates, is spread, interpreted, and implemented. They also offer food for thought on the possibilities,
Hèla Yousfi
doaj   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

open access: yes, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco   +6 more
core   +3 more sources

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