Results 131 to 140 of about 353,465 (231)

Light‐Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression

Angewandte Chemie, EarlyView.
A photo‐triggered CRISPR/Cas12a machinery for gene editing is introduced. The machinery is applied for endogenous DNA methyltransferase 1 (DNMT1) gene editing and for in vitro disruption of the hepatocyte growth factor (HGF) gene. The machinery is used for in vivo knockout and disruption of the HGF gene in HepG2 tumors, resulting in effective apoptosis
Hong Liu, Jiantong Dong, Renzhi Wu, Jun Dai, Xiaoding Lou, Fan Xia, Itamar Willner, Fujian Huang   +7 more
wiley   +2 more sources

Erratum: [Corrigendum] Calcium efflux from the endoplasmic reticulum regulates cisplatin‑induced apoptosis in human cervical cancer HeLa cells. [PDF]

Oncol Lett
Shen L, Wen N, Xia M, Zhang Y, Liu W, Xu Y, Sun L.   +6 more
europepmc   +1 more source

Functional Dendrimer Nanogels for DNA Delivery and Gene Therapy of Tumors

Angewandte Chemie, EarlyView.
Dendrimer nanogels are designed by emulsion‐free method, endowing them with dual‐active groups, o‐hydroxyl amine, temperature‐responsiveness, polyampholyte property, and self‐triggered aminolysis. With these unique characters, dendrimer nanogels display high gene transfection and therapeutic efficacies with low side effects, thus solving the dilemma ...
Xin Li, Zhijun Ouyang, Laura Hetjens, Ming Ni, Kuailu Lin, Yong Hu, Xiangyang Shi, Andrij Pich   +7 more
wiley   +2 more sources

Stilbene Glycosides in <i>Pinus cembra</i> L. Bark: Isolation, Characterization, and Assessment of Antioxidant Potential and Antitumor Activity on HeLa Cells. [PDF]

Plants (Basel)
Lungu C, Mihai CT, Vochita G, Gherghel D, Mangalagiu II, Gafton M, Miron SD, Iurciuc Tincu CE, Nahar L, Sarker SD, Miron A.   +10 more
europepmc   +1 more source

Potential Mechanisms of Metformin-Induced Apoptosis in HeLa Cells. [PDF]

Biomolecules, 2023
Chu Z, Tan Y, Xu C, Zhangsun D, Zhu X.
europepmc   +1 more source

Maturation of 5.8 S RNA in HeLa cells [PDF]

FEBS Letters, 1976
M.S.N. Khan, B.E.H. Maden
openaire   +3 more sources

A Hypoxia‐Triggered Bioreduction of Hydrophilic Type I Photosensitizer for Switchable In Vivo Photoacoustic Imaging and High‐Specificity Cancer Phototherapy

Angewandte Chemie, EarlyView.
A hydrophilic type I phototherapeutic agent (NanoPcN8O) was developed which selectively responded to hypoxic tumor microenvironments and switched on type I photodynamic and photothermal effects as well as a photoacoustic signal for activatable photoacoustic imaging and tumor phototherapy.
Yuan‐Yuan Zhao, Yihui Xu, Xiaojun Zhang, Zixuan Chen, Heejeong Kim, Xingshu Li, Juyoung Yoon   +6 more
wiley   +2 more sources

On the Synergistic Effects of Cold Atmospheric Pressure Plasma Irradiation and Electroporation on Cytotoxicity of HeLa Cells. [PDF]

Int J Mol Sci
Kitajima N, Makihara K, Kurita H.
europepmc   +1 more source

Proto-oncogene DEK binds to pre-mRNAs and regulates the alternative splicing of Hippo signaling genes in HeLa cells. [PDF]

Mol Genet Genomics
Liu D, Sun W, Han J, Wang C, Chen D, Wu Y, Chang Y, Yang B.   +7 more
europepmc   +1 more source

Phosphate (Pi) Transporter PIT1 Induces Pi Starvation in Salmonella-Containing Vacuole in HeLa Cells. [PDF]

Int J Mol Sci, 2023
Yang W, Feng Y, Yan J, Kang C, Yao T, Sun H, Cheng Z.   +6 more
europepmc   +1 more source